isoquercetin
Small moleculeexperimental
Clinical trial activity
7 trials · 12 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
7
Phase 3
1
Phase 4
0
Earliest trial started Jun 1, 2020 (NCT04622865)
Timeline
Indications
Mechanism of action
- Xanthine dehydrogenaseINHIBITOR
XDH inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
O=c1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12- Mol. weight
- 464.38 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL250450 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07303894 | Phase 2 | Jan 31, 2026 | Memorial Sloan-Kettering Cancer Center, National Institutes of Health (NIH) |
| NCT06861088 | Phase 3 | Jun 30, 2025 | Quercis Pharma AG |
| NCT04733651 | Phase 2 | Feb 20, 2021 | Government of Nepal |
| NCT04474626 | Phase 2 | Dec 31, 2020 | Harvard University, Quercegen Pharmaceuticals |
| NCT04536090 | Phase 2 | Nov 30, 2020 | McGill University, Pharmasciences, Quercis Pharma AG, SCiAN Services, Inc. |
| NCT04514510 | Phase 2 | Nov 2, 2020 | National Heart, Lung, and Blood Institute (NHLBI) |
| NCT04622865 | Phase 2 | Jun 1, 2020 | AB Science, Aix-Marseille University |
Showing 7 of 7 trials
Page 1 / 1
Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Quercis Pharma AG | For profit | 2 | 1 | 2 | 2020 |
| AB Science | For profit | 1 | 1 | 1 | 2020 |
| Aix-Marseille University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Government of Nepal | Government | 1 | 1 | 1 | 2021 |
| Harvard University | Academic/Hospital | 1 | 1 | 1 | 2020 |
| McGill University | Academic/Hospital | 1 | 1 | 1 | 2020 |
| Memorial Sloan-Kettering Cancer Center | Academic/Hospital | 1 | 1 | 1 | 2026 |
| National Heart, Lung, and Blood Institute (NHLBI) | Government | 1 | 1 | 1 | 2020 |
| National Institutes of Health (NIH) | Government | 1 | 0 | 1 | 2026 |
| Pharmasciences | For profit | 1 | 0 | 1 | 2020 |
| Quercegen Pharmaceuticals | For profit | 1 | 0 | 1 | 2020 |
| SCiAN Services, Inc. | For profit | 1 | 0 | 1 | 2020 |
12 organizations
Page 1 / 1