epicatechin

Small moleculeexperimental

Catechin is a flavan-3-ol, a type of secondary metabolite providing antioxidant roles in plants. It belongs to the subgroup of polyphenols called flavonoids. — Wikipedia

Clinical trial activity

41 trials · 52 clinical orgs · 0 marketing orgs

Phase 1

Phase 2

Phase 3

Phase 4

Earliest trial started Nov 1, 2005 (NCT00239213)

Timeline

2000s

Jan 1, 2006
Earliest Phase 1 Sponsor(trial)

2010s

Jan 1, 2012
Earliest Phase 2 Sponsor(trial)
Jan 1, 2019
Earliest Phase 3 Sponsor(trial)

Mechanism of action

Unspecified targetAntioxidant
antioxidant

Chemistry & pharmacology

Loading structure…

SMILES

Oc1cc(O)c2c(c1)O[C@@H](c1ccc(O)c(O)c1)[C@@H](O)C2

Mol. weight: 290.27 g/mol
Lipinski Ro5: Pass
Rule of 3: No
Chirality: Single Stereoisomer
Inorganic: No
Polymer: No

Oral

Parenteral

Topical

Sources

Also known as

catechin
catechin
catechin
catechin extracts
catechins
catechins
catechu
catechu
epicatechin
epicatechin
epicatechin
(-)-epicatechin
(-)-epicatechin
(+)-epicatechin
(+)-epicatechin
tea catechin extracts

Clinical trials

NCT ID	Phase	Start date	Sponsor(s)
NCT07149506	Phase 3	Sep 1, 2025	Hospital Regional Alta Especialidad Bajio, Universidad de Guanajuato
NCT06631820	N/A	Nov 30, 2024	Karolinska Institute
NCT05113498	N/A	Nov 30, 2021	Ghent University
NCT04597359	Phase 2	Jan 1, 2021	ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)
NCT04386304	Phase 1	Jun 30, 2020	Epirium Bio Inc.
NCT04055142	Phase 3	Sep 30, 2019	Universidad Autonoma de Barcelona
NCT03682601	Phase 4	Aug 30, 2018	GTO Pharmaceutical, LLC, New York University
NCT03213340	N/A	Sep 14, 2017	Abbott
NCT03123068	Phase 1/Phase 2 (Phase 2)	Apr 17, 2017	Stanford University
NCT03236662	Phase 2	Nov 30, 2016	University of California, Davis
NCT02943096	N/A	Nov 1, 2016	Columbia University
NCT02964377	Phase 1/Phase 2 (Phase 2)	Nov 1, 2016	Cardero Therapeutics, Inc., University of California, Davis
NCT02660112	Phase 2	Sep 1, 2016	Cardero Therapeutics, Inc., Mayo Clinic
NCT03194620	N/A	Aug 31, 2016	Mars, Inc., University of California, Davis
NCT02898571	N/A	Jul 1, 2016	Linkoping University, Newcastle University
NCT02656212	Phase 1	Sep 1, 2015	Department of Veteran Affairs, National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health (NIH), University of California, San Diego, Veterans Medical Research Foundation
NCT02490527	N/A	Jun 1, 2015	American Heart Association, University of California, San Diego
NCT02330276	Phase 1	Sep 1, 2014	Department of Veteran Affairs, National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health (NIH), University of California, San Diego, Veterans Medical Research Foundation
NCT02013856	N/A	Jul 1, 2014	Quadram Institute
NCT02221791	N/A	Jun 1, 2014	Top Institute Food and Nutrition, Wageningen University

Showing 20 of 41 trials

Page 1 / 3

Organizations

Research & Development (52)

Organization	Org type	Trials	As lead sponsor	Phases	Earliest year
Primus Pharmaceuticals	For profit	5	4	2	2006
University of California, San Diego	Academic/Hospital	5	3	2	2012
University of Shizuoka	Academic/Hospital	5	5	1	2005
University of California, Davis	Academic/Hospital	4	4	2	2013
Cardero Therapeutics, Inc.	For profit	3	0	1	2013
Danisco	For profit	2	1	2	2010
Department of Veteran Affairs	Government	2	0	1	2014
Mars, Inc.	For profit	2	0	1	2009
MIMA Century Research Associates	For profit	2	0	1	2006
National Center for Complementary and Integrative Health (NCCIH)	Government	2	0	1	2014
National Institutes of Health (NIH)	Government	2	0	1	2014
Quadram Institute	Academic/Hospital	2	2	1	2010
Seirei Hamamatsu General Hospital	Academic/Hospital	2	0	1	2005
Sun Valley Arthritis Ltd, Glendale	Academic/Hospital	2	0	1	2006
Top Institute Food and Nutrition	Academic/Hospital	2	0	1	2012
Veterans Medical Research Foundation	Academic/Hospital	2	2	1	2014
Wageningen University	Academic/Hospital	2	2	1	2012
White Cross Nursing Home	Academic/Hospital	2	0	1	2005
4Pharma Ltd.	For profit	1	0	1	2012
Abbott	For profit	1	1	1	2017

52 organizations