acebilustat
Small moleculeexperimental
Clinical trial activity
9 trials · 13 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
5
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2012 (NCT01748838)
Timeline
Indications
Mechanism of action
- Leukotriene A-4 hydrolaseINHIBITOR
LTA4H inhibitor
- Leukotriene A4 hydrolaseINHIBITOR
Leukotriene A4 hydrolase inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
O=C(O)c1ccc(CN2C[C@@H]3C[C@H]2CN3Cc2ccc(Oc3ccc(-c4ncco4)cc3)cc2)cc1- Mol. weight
- 481.55 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4297604 ↗
Also known as
- ctx-4430
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05203835 | Phase 2 | Jul 27, 2022 | Celltaxis LLC, Stanford University |
| NCT04662086 | Phase 2 | Apr 23, 2021 | Stanford University |
| NCT04662060 | Phase 2 | Jan 31, 2021 | Stanford University |
| NCT03964558 | Phase 1 | Apr 1, 2019 | Celtaxsys, Inc., Quotient |
| NCT02443688 | Phase 2 | Oct 1, 2015 | Celtaxsys, Inc., University of Alabama, Birmingham, University of London |
| NCT02385760 | Phase 2 | Apr 1, 2015 | Celtaxsys, Inc., Clinical Neuroscience Solutions, Inc., Veracity Clinical Research |
| NCT02233244 | Phase 1 | Sep 1, 2014 | Celerion, Celtaxsys, Inc. |
| NCT01944735 | Phase 1 | Sep 1, 2013 | Celerion, Celtaxsys, Inc., Queen's University, Belfast |
| NCT01748838 | Phase 1 | Dec 1, 2012 | Celtaxsys, Inc., Clinical Network Services, CPR Pharma Services Pty Ltd, Australia, Linear Clinical Research |
Showing 9 of 9 trials
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Organizations
Research & Development (13)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Celtaxsys, Inc. | For profit | 6 | 6 | 2 | 2012 |
| Stanford University | Academic/Hospital | 3 | 3 | 1 | 2021 |
| Celerion | For profit | 2 | 0 | 1 | 2013 |
| Celltaxis LLC | For profit | 1 | 0 | 1 | 2022 |
| Clinical Network Services | For profit | 1 | 0 | 1 | 2012 |
| Clinical Neuroscience Solutions, Inc. | For profit | 1 | 0 | 1 | 2015 |
| CPR Pharma Services Pty Ltd, Australia | For profit | 1 | 0 | 1 | 2012 |
| Linear Clinical Research | For profit | 1 | 0 | 1 | 2012 |
| Queen's University, Belfast | Academic/Hospital | 1 | 0 | 1 | 2013 |
| Quotient | For profit | 1 | 0 | 1 | 2019 |
| University of Alabama, Birmingham | Academic/Hospital | 1 | 0 | 1 | 2015 |
| University of London | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Veracity Clinical Research | For profit | 1 | 0 | 1 | 2015 |
13 organizations
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