elsulfavirine
Trade name: Elpida
Small moleculeexperimental
Clinical trial activity
14 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
12
Phase 2
2
Phase 3
2
Phase 4
0
Earliest trial started Jul 1, 2012 (NCT02489435)
Timeline
Indications
Mechanism of action
- Reverse transcriptaseINHIBITOR
Reverse transcriptase inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CCC(=O)NS(=O)(=O)c1ccc(NC(=O)Cc2ccc(Br)c(Oc3cc(Cl)cc(C#N)c3)c2F)c(Cl)c1- Mol. weight
- 629.29 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4301163 ↗
Also known as
- vm-1500
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05204394 | Phase 2/Phase 3 (Phase 3) | Apr 1, 2022 | Government of Russia, Viriom |
| NCT05165550 | Phase 1 | Dec 15, 2021 | Altasciences Company Inc., Viriom |
| NCT05148754 | Phase 1 | Jan 23, 2021 | Government of Russia, Viriom |
| NCT05163535 | Phase 1/Phase 2 (Phase 2) | Jan 19, 2021 | Government of Russia, Viriom |
| NCT03730311 | Phase 1 | May 31, 2019 | Siriraj Hospital, Viriom |
| NCT03706911 | Phase 1 | Dec 31, 2018 | I.M. Sechenov First Moscow State Medical University, Viriom |
| NCT05204121 | Phase 1 | Dec 18, 2018 | I.M. Sechenov First Moscow State Medical University, Viriom |
| NCT03709355 | Phase 1 | Oct 31, 2018 | I.M. Sechenov First Moscow State Medical University, Smolensk Region Clinical Hospital, Viriom |
| NCT03706898 | Phase 1 | Oct 1, 2018 | Viriom |
| NCT03706924 | Phase 1 | Jun 1, 2018 | Viriom |
| NCT02489487 | Phase 1 | Sep 1, 2014 | Viriom |
| NCT02489461 | Phase 2/Phase 3 (Phase 3) | Aug 1, 2014 | Viriom |
| NCT02485509 | Phase 1/Phase 2 (Phase 2) | Mar 1, 2013 | Viriom |
| NCT02489435 | Phase 1 | Jul 1, 2012 | Viriom |
Showing 14 of 14 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Viriom | For profit | 14 | 14 | 3 | 2012 |
| Government of Russia | Government | 3 | 0 | 3 | 2021 |
| I.M. Sechenov First Moscow State Medical University | Academic/Hospital | 3 | 0 | 1 | 2018 |
| Altasciences Company Inc. | For profit | 1 | 0 | 1 | 2021 |
| Siriraj Hospital | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Smolensk Region Clinical Hospital | Academic/Hospital | 1 | 0 | 1 | 2018 |
6 organizations
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