podophyllin
Biologicalexperimental
Podophyllum resin, also known as podophyllum or podophyllin, is a resin made from the roots of the American mandrake. It is used as a medication to treat genital warts and plantar warts, including in people with HIV/AIDS. It is not recommended in HPV infections without external warts. Application by a healthcare provider to the skin is recommended. — Wikipedia
Clinical trial activity
2 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
2
Phase 3
1
Phase 4
0
Earliest trial started Feb 29, 2020 (NCT03853785)
Timeline
Indications
Mechanism of action
- TubulinINHIBITOR
Tubulin inhibitor
- Tubulin beta-4B chain (TUBB4B) ↗
- Tubulin beta-1 chain (TUBB1) ↗
- Tubulin alpha-3C chain (TUBA3C) ↗
- Tubulin alpha-4A chain (TUBA4A) ↗
- Tubulin beta-3 chain (TUBB3) ↗
- Tubulin alpha-1A chain (TUBA1A) ↗
- Tubulin beta-4A chain (TUBB4A) ↗
- Tubulin beta-8 chain (TUBB8) ↗
- Tubulin beta chain (TUBB) ↗
- Tubulin alpha-1B chain (TUBA1B) ↗
- Tubulin alpha-1C chain (TUBA1C) ↗
- Tubulin alpha-3E chain (TUBA3E) ↗
- Tubulin beta-2A chain (TUBB2A) ↗
- Tubulin beta-2B chain (TUBB2B) ↗
- Tubulin beta-6 chain (TUBB6) ↗
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPodophyllum resin ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06809777 | Phase 2 | Jan 29, 2025 | Sheikh Zayed Medical College |
| NCT03853785 | Phase 3 | Feb 29, 2020 | Assiut University |
Showing 2 of 2 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Assiut University | Academic/Hospital | 1 | 1 | 1 | 2020 |
| Sheikh Zayed Medical College | Academic/Hospital | 1 | 1 | 1 | 2025 |
2 organizations
Page 1 / 1