tti-101
Small moleculeexperimental
Clinical trial activity
7 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
6
Phase 2
5
Phase 3
0
Phase 4
0
Earliest trial started Nov 15, 2017 (NCT03195699)
Timeline
Indications
Studied for
- Breast Neoplasms · Phase 1/Phase 2
- Carcinoma, Hepatocellular · Phase 1/Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 1
- Colorectal Neoplasms · Phase 1
- Idiopathic Pulmonary Fibrosis · Phase 2
- Liver Neoplasms · Phase 1
- Melanoma · Phase 1
- Neoplasms · Phase 1
- Pancreatic Neoplasms · Phase 1/Phase 2
- Squamous Cell Carcinoma of Head and Neck · Phase 1/Phase 2
- Stomach Neoplasms · Phase 1
Mechanism of action
STAT3 inhibitor
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05845307 | Early Phase 1 (Phase 1) | Oct 31, 2024 | National Institutes of Health (NIH), Tvardi Therapeutics, Incorporated, University of Texas at Houston |
| NCT06141031 | Phase 1/Phase 2 (Phase 2) | Dec 31, 2023 | Tvardi Therapeutics, Incorporated, University of Colorado, Denver |
| NCT05668949 | Phase 1/Phase 2 (Phase 2) | Jun 30, 2023 | Tvardi Therapeutics, Incorporated, University of Texas at Houston |
| NCT05671835 | Phase 2 | May 15, 2023 | Tvardi Therapeutics, Incorporated |
| NCT05384119 | Phase 1/Phase 2 (Phase 2) | Nov 30, 2022 | Tvardi Therapeutics, Incorporated |
| NCT05440708 | Phase 1/Phase 2 (Phase 2) | Nov 30, 2022 | Tvardi Therapeutics, Incorporated |
| NCT03195699 | Phase 1 | Nov 15, 2017 | Tvardi Therapeutics, Incorporated, University of Texas at Houston |
Showing 7 of 7 trials
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Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Tvardi Therapeutics, Incorporated | For profit | 7 | 4 | 2 | 2017 |
| University of Texas at Houston | Academic/Hospital | 3 | 2 | 2 | 2017 |
| National Institutes of Health (NIH) | Government | 1 | 0 | 1 | 2024 |
| University of Colorado, Denver | Academic/Hospital | 1 | 1 | 1 | 2023 |
4 organizations
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