bacillus cereus

Cell therapyexperimental

Bacillus cereus is a Gram-positive rod-shaped bacterium commonly found in soil, food, and marine sponges. The specific name, cereus, meaning "waxy" in Latin, refers to the appearance of colonies grown on blood agar. Some strains are harmful to humans and cause foodborne illness due to their spore-forming nature, while other strains can be beneficial as probiotics for animals, and even exhibit mutualism with certain plants. B. cereus bacteria may be aerobes or facultative anaerobes, and like other members of the genus Bacillus, can produce protective endospores. They have a wide range of virulence factors, including phospholipase C, cereulide, sphingomyelinase, metalloproteases, and cytotoxin K, many of which are regulated via quorum sensing. B. cereus strains exhibit flagellar motility. — Wikipedia

Clinical trial activity

2 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
1

Earliest trial started Apr 15, 2018 (NCT03486587)

Timeline

2010s

  1. Jan 1, 2018

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Mechanism of action

  • microbiotaTissue restoration

    microbiota tissue restoration

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04982380Phase 4Jul 31, 2021Chengde Medical University, Chinese Academy of Medical Sciences, Hangzhou Grand Biologic Pharmaceutical, Inc., Harbin Medical University, Inner Mongolia Medical University, Zhengzhou University
NCT03486587Phase 2Apr 15, 2018Sun Yat-Sen University
Showing 2 of 2 trials
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Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Chengde Medical UniversityAcademic/Hospital1012021
Chinese Academy of Medical SciencesAcademic/Hospital1112021
Hangzhou Grand Biologic Pharmaceutical, Inc.Government1012021
Harbin Medical UniversityAcademic/Hospital1012021
Inner Mongolia Medical UniversityAcademic/Hospital1012021
Sun Yat-Sen UniversityAcademic/Hospital1112018
Zhengzhou UniversityAcademic/Hospital1012021
7 organizations
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