yimitasvir
Small moleculeexperimental
Clinical trial activity
8 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
4
Phase 3
2
Phase 4
0
Earliest trial started Dec 3, 2014 (NCT03462173)
Timeline
Indications
Mechanism of action
- Genome polyproteinINHIBITOR
Genome polyprotein inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc(-c4ccc5nc([C@@H]6CCCN6C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]c5c4)c4c3[C@@H]3CC[C@H]4C3)cc2)[nH]1)C(C)C- Mol. weight
- 855.05 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5095204 ↗
- ChEMBLCHEMBL5095203 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04565171 | Phase 1 | Oct 20, 2020 | Sichuan University, Sunshine Lake Pharma Co., Ltd. |
| NCT04552808 | Phase 1 | Sep 8, 2020 | Sunshine Lake Pharma Co., Ltd. |
| NCT04155515 | Phase 3 | Jun 13, 2019 | TaiGen Biotechnology Co., Ltd. |
| NCT03487107 | Phase 3 | Apr 3, 2018 | Peking University, Sunshine Lake Pharma Co., Ltd. |
| NCT03593447 | Phase 2 | Mar 15, 2018 | Peking University, TaiGen Biotechnology Co., Ltd. |
| NCT03610880 | Phase 1 | Oct 17, 2017 | Central South University, R&G Pharma Studies Co.,Ltd., TaiGen Biotechnology Co., Ltd. |
| NCT03458481 | Phase 2 | Jul 31, 2017 | Peking University, Sunshine Lake Pharma Co., Ltd. |
| NCT03462173 | Phase 1 | Dec 3, 2014 | Peking University, Sunshine Lake Pharma Co., Ltd. |
Showing 8 of 8 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Sunshine Lake Pharma Co., Ltd. | For profit | 5 | 5 | 3 | 2014 |
| Peking University | Academic/Hospital | 4 | 0 | 3 | 2014 |
| TaiGen Biotechnology Co., Ltd. | For profit | 3 | 3 | 3 | 2017 |
| Central South University | Academic/Hospital | 1 | 0 | 1 | 2017 |
| R&G Pharma Studies Co.,Ltd. | For profit | 1 | 0 | 1 | 2017 |
| Sichuan University | Academic/Hospital | 1 | 0 | 1 | 2020 |
6 organizations
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