Povorcitinib

Small moleculeexperimental

Clinical trial activity

23 trials · 1 clinical orgs · 0 marketing orgs

Phase 1
7
Phase 2
16
Phase 3
8
Phase 4
0

Earliest trial started Jun 11, 2018 (NCT03569371)

Timeline

2010s

  1. Jan 1, 2018

    Earliest Phase 2 Sponsor(trial)

2020s

  1. Jan 1, 2021

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2022

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Cc1n[nH]c(C)c1-c1cnn(C2(CC#N)CN(c3cc(F)c(C(=O)N[C@@H](C)C(F)(F)F)cc3F)C2)c1
Mol. weight
507.47 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07213973Phase 2Dec 14, 2025Incyte
NCT06855498Phase 3Feb 28, 2025Incyte
NCT06516965Phase 3Oct 10, 2024Incyte
NCT06516952Phase 3Oct 10, 2024Incyte
NCT06505265Phase 1Aug 12, 2024Incyte
NCT06441318Phase 1Jul 12, 2024Incyte
NCT06416800Phase 1Jun 19, 2024Incyte
NCT06380205Phase 1May 7, 2024Incyte
NCT06212999Phase 3Jan 30, 2024Incyte
NCT06113445Phase 3Nov 29, 2023Incyte
NCT06113471Phase 3Nov 27, 2023Incyte
NCT05936567Phase 2Jul 31, 2023Incyte
NCT05851443Phase 2Jul 11, 2023Incyte
NCT05624710Phase 1Feb 26, 2023Incyte
NCT05620836Phase 3Dec 14, 2022Incyte
NCT05620823Phase 3Dec 14, 2022Incyte
NCT05624723Phase 1Nov 17, 2022Incyte
NCT05061693Phase 2Nov 17, 2021Incyte
NCT05068466Phase 1Oct 21, 2021Incyte
NCT04818346Phase 2May 6, 2021Incyte
Showing 20 of 23 trials
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Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
IncyteFor profit232332018
1 organizations
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