afimetoran

Small moleculeexperimental

Clinical trial activity

11 trials · 1 clinical orgs · 0 marketing orgs

Phase 1
10
Phase 2
1
Phase 3
0
Phase 4
0

Earliest trial started Aug 3, 2018 (NCT03634995)

Timeline

2010s

  1. Jan 1, 2018

    Earliest Phase 1 Sponsor(trial)

2020s

  1. Jan 1, 2021

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Cc1c(-c2[nH]c3ccc(C4CCN(CC(N)=O)CC4)cc3c2C(C)C)cn2ncnc2c1C
Mol. weight
444.58 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05866627Phase 1Jul 4, 2023Bristol-Myers Squibb
NCT05901714Phase 1Jun 19, 2023Bristol-Myers Squibb
NCT04895696Phase 2Jun 30, 2021Bristol-Myers Squibb
NCT04941755Phase 1Jun 25, 2021Bristol-Myers Squibb
NCT04493541Phase 1Aug 27, 2020Bristol-Myers Squibb
NCT04470778Phase 1Jul 20, 2020Bristol-Myers Squibb
NCT04269356Phase 1Feb 14, 2020Bristol-Myers Squibb
NCT04039373Phase 1Jul 22, 2019Bristol-Myers Squibb
NCT04016753Phase 1Jul 3, 2019Bristol-Myers Squibb
NCT03950960Phase 1May 17, 2019Bristol-Myers Squibb
NCT03634995Phase 1Aug 3, 2018Bristol-Myers Squibb
Showing 11 of 11 trials
Page 1 / 1

Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Bristol-Myers SquibbFor profit111122018
1 organizations
Page 1 / 1