sodium carbonate

Small moleculeapproved

Approved

Jun 22, 1982

Potash (Dihydroxyaluminum Sodium Carbonate), a component of Kompensan-S Forte in Germany, is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions. Kompensan-S Forte is slowly solubilized in the stomach and reacts with hydrochloric acid to form aluminum chloride and water. It also inhibits the action of pepsin by increasing the pH and via adsorption. Cytoprotective effects may occur through increases in bicarbonate ion (HCO3-) and prostaglandins. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 3 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Timeline

1980s

  1. Jun 22, 1982

    Baxter — Earliest FDA Approval

  2. Jun 22, 1982

    Baxalta — NDA Secondary Org

  3. Jun 22, 1982

    Baxter — NDA Secondary Org

  4. Jun 22, 1982

    Baxter — NDA Organization

  5. Mar 15, 1984

    Hospira — NDA Secondary Org

Indications

Mechanism of action

  • Unspecified targetBuffer

    buffer

Combination products

Approval history

  • approvedJun 22, 1982

Chemistry & pharmacology

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SMILES

[O-]C([O-])=O
Mol. weight
60.0089 g/mol

Oral

No

Parenteral

No

Topical

No

Sources

Organizations

Marketing (4)

OrganizationOrg typeRelationshipDate
BaxaltaFor profitNDA2Jun 22, 1982
BaxterFor profitNDA2Jun 22, 1982
BaxterFor profitNDAJun 22, 1982
HospiraFor profitNDA2Mar 15, 1984