belotecan
Small moleculeexperimental
Clinical trial activity
8 trials · 18 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
7
Phase 3
1
Phase 4
0
Earliest trial started Sep 1, 2003 (NCT00177281)
Timeline
Indications
Mechanism of action
- DNA topoisomerase IINHIBITOR
TOP1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CCNC(C)C- Mol. weight
- 433.51 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2111084 ↗
- ChEMBLCHEMBL2107315 ↗
Also known as
- 7-(2-(n-isopropylamino)ethyl)camptothecin
- belotecan
- belotecan
- belotecan
- belotecan
- belotecan
- belotecan
- belotecan
- belotecan
- belotecan hcl
- belotecan hcl
- belotecan hydrochloride
- belotecan hydrochloride
- belotecan hydrochloride
- belotecan hydrochloride
- camtobell
- ckd602
- ckd602
- ckd602
- ckd602
- ckd 602
- ckd-602
- ckd-602
- ckd-602
- ckd-602
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01784107 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2011 | Gachon University |
| NCT01630018 | Phase 2 | Jan 1, 2011 | Chong Kun Dang Pharmaceutical, Seoul National University |
| NCT01497873 | Phase 2 | Sep 1, 2010 | Ajou University, Catholic University of Korea, Chonbuk National University, Chong Kun Dang Pharmaceutical, Chung-Ang University, Keimyung University, Kyung Hee University, Seoul National University, Seoul Veterans Hospital, The National Cancer Center, University of Ulsan, Yonsei University |
| NCT01022671 | Phase 2 | Sep 1, 2009 | Chong Kun Dang Pharmaceutical, Seoul National University, Sungkyunkwan University, University of Ulsan |
| NCT00826644 | Phase 3 | Jan 1, 2009 | Chong Kun Dang Pharmaceutical, Chonnam National University |
| NCT00754858 | Phase 2 | Oct 1, 2008 | Yonsei University |
| NCT00430144 | Phase 2 | Jan 1, 2007 | National Cancer Center, Korea, The National Cancer Center |
| NCT00177281 | Phase 1 | Sep 1, 2003 | Alza, University of Pittsburgh |
Showing 8 of 8 trials
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Organizations
Research & Development (18)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Chong Kun Dang Pharmaceutical | For profit | 4 | 3 | 2 | 2009 |
| Seoul National University | Academic/Hospital | 3 | 0 | 1 | 2009 |
| The National Cancer Center | Academic/Hospital | 2 | 0 | 1 | 2007 |
| University of Ulsan | Academic/Hospital | 2 | 0 | 1 | 2009 |
| Yonsei University | Academic/Hospital | 2 | 1 | 1 | 2008 |
| Ajou University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Alza | For profit | 1 | 0 | 1 | 2003 |
| Catholic University of Korea | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Chonbuk National University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Chonnam National University | Academic/Hospital | 1 | 1 | 1 | 2009 |
| Chung-Ang University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Gachon University | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Keimyung University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Kyung Hee University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| National Cancer Center, Korea | Government | 1 | 1 | 1 | 2007 |
| Seoul Veterans Hospital | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Sungkyunkwan University | Academic/Hospital | 1 | 0 | 1 | 2009 |
| University of Pittsburgh | Academic/Hospital | 1 | 1 | 1 | 2003 |
18 organizations
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