gacyclidine

Small moleculeexperimental

Gacyclidine is a psychoactive drug which acts as a dissociative via functioning as a non-competitive NMDA receptor antagonist. It is closely related to phencyclidine (PCP), and specifically, is a derivative of tenocyclidine (TCP). — Wikipedia

Clinical trial activity

2 trials · 1 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
2
Phase 3
0
Phase 4
0

Earliest trial started Apr 4, 2019 (NCT03918109)

Timeline

2010s

  1. Jan 1, 2019

    Earliest Phase 1 Sponsor(trial)

2020s

  1. Jan 1, 2021

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CC1CCCCC1(c1cccs1)N1CCCCC1
Mol. weight
263.45 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Racemic Mixture
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • gacyclidine

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04829214Phase 2Mar 22, 2021Otonomy, Inc.
NCT03918109Phase 1/Phase 2 (Phase 2)Apr 4, 2019Otonomy, Inc.
Showing 2 of 2 trials
Page 1 / 1

Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Otonomy, Inc.For profit2212019
1 organizations
Page 1 / 1