parnaparin
Parnaparin is an antithrombotic and belongs to the group of low molecular weight heparins. In the prevention and therapy of thromboembolic pathologies, the advent of this class of drugs represented a medical development, since they retain the same effectiveness of unfractionated heparin but with simpler dosing regimens and decreased side effects. In addition to being effective in treating proven deep vein thrombosis and thrombosis-associated phlebopathies, Parnaparin has demonstrated its thromboprophylactic efficacy in both high- and moderate-risk surgical patients. — Wikipedia
Clinical trial activity
2 trials · 5 clinical orgs · 0 marketing orgs
Earliest trial started Jul 1, 2002 (NCT00732927)
Timeline
2000s
- Jan 1, 2002
Earliest Phase 3 Sponsor(trial)
Indications
Mechanism of action
Coagulation factor X/antithrombin III activator
- Antithrombin-IIIACTIVATOR
Antithrombin-III activator
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaParnaparin sodium ↗
- ChEMBLCHEMBL3707207 ↗
- ChEMBLCHEMBL2108080 ↗
Also known as
- op-21-23
- parnaparin
- parnaparin
- parnaparin
- parnaparin
- parnaparin
- parnaparin sodium
- parnaparin sodium
- parnaparin sodium
- parnaparin sodium
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02991950 | Phase 3 | Jul 1, 2011 | Istituto Clinico Humanitas - Rozzano (MI), Italy |
| NCT00732927 | Phase 3 | Jul 1, 2002 | Alfa Wassermann, Ospedale di Gallarate, Ospedale di Piacenza, University of Insubria |
Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Alfa Wassermann | For profit | 1 | 0 | 1 | 2002 |
| Istituto Clinico Humanitas - Rozzano (MI), Italy | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Ospedale di Gallarate | Academic/Hospital | 1 | 0 | 1 | 2002 |
| Ospedale di Piacenza | Academic/Hospital | 1 | 0 | 1 | 2002 |
| University of Insubria | Academic/Hospital | 1 | 1 | 1 | 2002 |