pranoprofen
Small moleculeexperimental
Pranoprofen (INN) is a nonsteroidal anti-inflammatory drug (NSAID) used in ophthalmology. — Wikipedia
Clinical trial activity
3 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
2
Earliest trial started Jan 1, 2016 (NCT03712670)
Timeline
No events for the selected filters.
Indications
Approved for
Studied for
Mechanism of action
- Cyclooxygenase-2INHIBITOR
PTGS2 inhibitor
- Cyclooxygenase-1INHIBITOR
PTGS1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CC(C(=O)O)c1ccc2c(c1)Cc1cccnc1O2- Mol. weight
- 255.27 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPranoprofen ↗
- ChEMBLCHEMBL367463 ↗
Also known as
- 2-(5h-(1)benzopyrano(2,3-b)pyridin-7-yl)propionic acid
- alcon brand of pranoprofen
- dl-pranoprofen
- niflan
- niflan
- nifran
- oftalar
- oftalar
- pranoprofen
- pranoprofen
- pranoprofen
- pranoprofen
- pranoprofen
- pranoprofen
- pranoprofen
- pyranoprofen
- pyranoprofen, methyl-14c-labeled
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07291089 | Phase 4 | Feb 23, 2024 | Jiao Tong University |
| NCT03355638 | Phase 4 | Jan 31, 2016 | University of Brescia |
| NCT03712670 | N/A | Jan 1, 2016 | University of Brescia |
Showing 3 of 3 trials
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Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Brescia | Academic/Hospital | 2 | 2 | 2 | 2016 |
| Jiao Tong University | Academic/Hospital | 1 | 1 | 1 | 2024 |
2 organizations
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