triprolidine
Trade name: Actidil
Approved
Jun 1, 1958
Triprolidine is a first generation histamine H1 antagonist, which in combination with codeine phosphate and pseudoephedrine hydrochloride is sold under brand name TRIACIN-C. TRIACIN-C is indicated for temporary relief of coughs and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 21 marketing orgs
Timeline
1950s
- Jun 1, 1958
Earliest FDA Approval
1970s
- Feb 7, 1977
Watson Pharmaceuticals — Marketing Organization
- Jul 13, 1979
Alpharma — Marketing Organization
1980s
- Jan 18, 1983
Upsher-Smith Laboratories — Marketing Organization
- Jul 13, 1983
West-Ward Pharmaceutical — Marketing Organization
- Sep 2, 1983
Sandoz — Marketing Organization
- Apr 20, 1984
Fondazione Golgi Cenci — Marketing Organization
- Nov 16, 1984
Wockhardt — Marketing Organization
- Dec 12, 1984
Teva — Marketing Organization
- Jan 17, 1985
Halsey — Marketing Organization
- Jan 31, 1985
Mylan — Marketing Organization
- Feb 12, 1985
Newtron Pharmaceuticals — Marketing Organization
- Mar 22, 1985
STI Pharma, LLC — Marketing Organization
- Mar 22, 1985
Animas Corporation — Marketing Organization
- Apr 11, 1985
Fosun — Marketing Organization
- Apr 11, 1985
Chartwell Pharmaceuticals — Marketing Organization
Indications
Mechanism of action
- Histamine H1 receptorANTAGONIST
HRH1 antagonist
Combination products
triacin-c
with codeine, pseudoephedrine
triprolidine and pseudoephedrine
with pseudoephedrine
Also known as allerfe, corphe, histafe, myfe, trilitron
Approval history
- approvedJun 1, 1958
Chemistry & pharmacology
SMILES
CC1=CC=C(C=C1)C(=C/CN2CCCC2)\C3=CC=CC=N3- Mol. weight
- 278.3914 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Availability
- Prescription Only
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaTriprolidine ↗
- NCATS2L8T9S52QM ↗
- ChEMBLCHEMBL855 ↗
- ChEMBLCHEMBL1200450 ↗
Also known as
- actahist
- actahist
- actidil
- actidil
- actidil
- actidil
- allerfed
- allerfed
- corphed
- corphed
- histafed
- histafed
- myfed
- myfed
- myidyl
- myidyl
- pro-actidil
- pro-actidil
- trilitron
- trilitron
- triphed
- triphed
- tripolidina
- tripolidina
- triprolidin
- triprolidin
- triprolidin
- triprolidine
- triprolidine
- triprolidine
- triprolidine
- triprolidine
- triprolidine
- triprolidine
- triprolidine hcl
- triprolidine hcl
- triprolidine hcl
- triprolidine hydrochloride
- triprolidine hydrochloride
- triprolidine hydrochloride
- triprolidine hydrochloride
- triprolidinum
- triprolidinum
- tripyrolidine
Organizations
Marketing (21)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Alpharma | For profit | MKTG | Jul 13, 1979 |
| Animas Corporation | For profit | MKTG | Mar 22, 1985 |
| Burroughs Wellcome | For profit | NDA | — |
| Chartwell Pharmaceuticals | For profit | MKTG | Apr 11, 1985 |
| Fondazione Golgi Cenci | Academic/Hospital | MKTG | Apr 20, 1984 |
| Fosun | For profit | MKTG | Apr 11, 1985 |
| GlaxoSmithKline | For profit | NDA2 | — |
| Halsey | For profit | MKTG | Jan 17, 1985 |
| Lumara Health | For profit | MKTG | — |
| Mylan | For profit | MKTG | Jan 31, 1985 |
| Newtron Pharmaceuticals | For profit | MKTG | Feb 12, 1985 |
| Pharmaceutical Associates | For profit | MKTG | — |
| STI Pharma, LLC | For profit | MKTG | Mar 22, 1985 |
| Sandoz | For profit | MKTG | Sep 2, 1983 |
| Superpharm | For profit | MKTG | — |
| Teva | For profit | MKTG | Dec 12, 1984 |
| Upsher-Smith Laboratories | For profit | MKTG | Jan 18, 1983 |
| Vitarine | For profit | MKTG | — |
| Watson Pharmaceuticals | For profit | MKTG | Feb 7, 1977 |
| West-Ward Pharmaceutical | For profit | MKTG | Jul 13, 1983 |
| Wockhardt | For profit | MKTG | Nov 16, 1984 |