protokylol
Trade name: ventaire
Small moleculeapproved
Approved
Jan 1, 1959
Protokylol, a sympathomimetic drug has been utilized in general clinical practice as a bronchodilator. Protokylol (brand names Caytine, Ventaire) is a β-adrenergic receptor agonist which was used as a bronchodilator in Europe and the United States. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 2 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
1950s
- Jan 1, 1959
Earliest FDA Approval
1960s
- Jul 20, 1965
Richardson Vicks Inc — First NDA Organization
- Jul 20, 1965
Richardson Vicks Inc — NDA Organization
Indications
Approved for
Mechanism of action
- Beta-2 adrenergic receptorAGONIST
ADRB2 agonist
Approval history
- approvedJan 1, 1959
Chemistry & pharmacology
Loading structure…
SMILES
CC(Cc1ccc2c(c1)OCO2)NCC(O)c1ccc(O)c(O)c1- Mol. weight
- 331.37 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
- Delivery
- Oral
- Availability
- Discontinued
Oral
Yes
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL1201273 ↗
- WikipediaProtokylol ↗
- NCATS8Y5Y4EEO2V ↗
- ChEMBLCHEMBL1200893 ↗
Also known as
- alpha-(alpha-methyl-3,4-methylenedioxyphenethylamino)methyl protocatechuyl alcohol
- asmeti
- asmeti
- asmetil
- caytine
- caytine
- caytine
- caytine
- jb-251
- palisan
- palisan
- protochilolo
- protochylol
- protokylol
- protokylol
- protokylol
- protokylol
- protokylol
- protokylol
- protokylol
- protokylol
- protokylol
- protokylol hcl
- protokylol hcl
- protokylol hcl
- protokylol hydrochloride
- protokylol hydrochloride
- protokylol hydrochloride
- protokylol hydrochloride
- protokylol hydrochloride
- ventaire
- ventaire
- ventaire
- ventaire
Organizations
Marketing (2)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Richardson Vicks Inc | For profit | NDA | Jul 20, 1965 |
| Sanofi-Aventis | For profit | MKTG | — |