sar-125844
Small moleculeexperimental
Clinical trial activity
3 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Jul 1, 2011 (NCT01391533)
Timeline
Indications
Studied for
Mechanism of action
- Hepatocyte growth factor receptorINHIBITOR
MET inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
O=C(NCCN1CCOCC1)Nc1nc2ccc(Sc3nnc4ccc(-c5ccc(F)cc5)nn34)cc2s1- Mol. weight
- 550.65 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4461070 ↗
- ChEMBLCHEMBL3545325 ↗
Also known as
- sar125844
- sar125844
- sar-125844
- sar-125844
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02435121 | Phase 2 | Nov 1, 2015 | Sanofi |
| NCT01657214 | Phase 1 | Sep 1, 2012 | Sanofi |
| NCT01391533 | Phase 1 | Jul 1, 2011 | Sanofi |
Showing 3 of 3 trials
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Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Sanofi | For profit | 3 | 3 | 2 | 2011 |
1 organizations
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