procaterol
Small moleculeexperimental
Procaterol is a β2 adrenoreceptor agonist used for the treatment of asthma in many countries, but is not approved in the United States. The drug is readily oxidized in the presence of moisture and air, and requires stabilizers for use by inhalation. — Wikipedia
Clinical trial activity
10 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
4
Phase 3
3
Phase 4
3
Earliest trial started May 1, 2006 (NCT00394485)
Timeline
Indications
Approved for
Mechanism of action
- Beta-2 adrenergic receptorAGONIST
ADRB2 agonist
Chemistry & pharmacology
Loading structure…
SMILES
CCC(NC(C)C)C(O)c1ccc(O)c2[nH]c(=O)ccc12- Mol. weight
- 290.36 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
- Availability
- Prescription Only
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL160519 ↗
- WikipediaProcaterol ↗
- ChEMBLCHEMBL1322218 ↗
- ChEMBLCHEMBL1201026 ↗
Also known as
- ci-888
- ci-888
- proair
- proair
- procaterol
- procaterol
- procaterol
- procaterol
- procaterol
- procaterol
- procaterol
- procaterol
- (+/-)-procaterol
- procaterol hcl
- procaterol hcl
- procaterol hydrochloride
- procaterol hydrochloride
- procaterol hydrochloride hemihydrate
- (r,s)-procaterol
- (r,s)-procaterol
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02349919 | N/A | Mar 1, 2015 | Mahidol University, Otsuka |
| NCT02162784 | Phase 2 | Feb 1, 2013 | Intech Biopharm Ltd. |
| NCT02165033 | Phase 1 | Nov 1, 2012 | Government of Taiwan, Intech Biopharm Ltd. |
| NCT02165046 | Phase 1 | Feb 1, 2012 | Government of Taiwan, Intech Biopharm Ltd. |
| NCT01170429 | Phase 4 | Jul 1, 2010 | Jiao Tong University |
| NCT01095016 | Phase 3 | Mar 1, 2010 | Chang Gung University, Otsuka |
| NCT01076322 | Phase 3 | Mar 1, 2009 | National Taiwan University, Otsuka |
| NCT00990847 | Phase 3 | Jun 1, 2007 | Otsuka, University of Indonesia |
| NCT00394485 | Phase 4 | May 1, 2006 | Otsuka, University of the Philippines |
| NCT01091337 | Phase 4 | May 1, 2006 | Otsuka, University of the Philippines |
Showing 10 of 10 trials
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Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Otsuka | For profit | 6 | 5 | 3 | 2006 |
| Intech Biopharm Ltd. | For profit | 3 | 3 | 2 | 2012 |
| Government of Taiwan | Government | 2 | 0 | 1 | 2012 |
| University of the Philippines | Academic/Hospital | 2 | 0 | 1 | 2006 |
| Chang Gung University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Jiao Tong University | Academic/Hospital | 1 | 1 | 1 | 2010 |
| Mahidol University | Academic/Hospital | 1 | 1 | 1 | 2015 |
| National Taiwan University | Academic/Hospital | 1 | 0 | 1 | 2009 |
| University of Indonesia | Academic/Hospital | 1 | 0 | 1 | 2007 |
9 organizations
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