plx-5622
Small moleculeexperimental
Clinical trial activity
2 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Jan 1, 2011 (NCT01282684)
Timeline
2010s
- Jan 1, 2011
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
CSF1R inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(C)cc23)c(F)n1- Mol. weight
- 395.41 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3639728 ↗
- ChEMBLCHEMBL3545079 ↗
Also known as
- plx5622
- plx-5622
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01329991 | Phase 1 | May 1, 2011 | Plexxikon |
| NCT01282684 | Phase 1 | Jan 1, 2011 | Plexxikon, PRACS |
Showing 2 of 2 trials
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