latrepirdine

Small moleculeexperimental

Latrepirdine is an antihistamine drug which has been used clinically in Russia since 1983. — Wikipedia

Clinical trial activity

28 trials · 5 clinical orgs · 0 marketing orgs

Phase 1
13
Phase 2
16
Phase 3
10
Phase 4
0

Earliest trial started Sep 1, 2005 (NCT00377715)

Timeline

2000s

  1. Jan 1, 2005

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2006

    Earliest Phase 1 Sponsor(trial)

  3. Jan 1, 2008

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(C)C1
Mol. weight
319.45 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)-ethyl)-1h-pyrid(4,3b)indole
  • dimebolin
  • dimebon
  • dimebon
  • dimebon
  • dimebon
  • dimebone
  • latrepirdine
  • latrepirdine
  • latrepirdine
  • latrepirdine
  • pf01913539
  • pf 01913539
  • pf-01913539
  • pf-01913539
  • pf-01913539
  • pf1913539
  • pf 1913539
  • pf-1913539

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06292351Phase 2Dec 27, 2023Bigespas LTD
NCT01066481Phase 2Apr 1, 2010Pfizer
NCT01152216Phase 3Apr 1, 2010Medivation, Pfizer
NCT01066546Phase 3Apr 1, 2010Medivation, Pfizer
NCT01085266Phase 3Feb 1, 2010Medivation, Pfizer
NCT00975481Phase 1Oct 1, 2009Medivation, Pfizer
NCT00990613Phase 1Oct 1, 2009Medivation, Pfizer
NCT00988624Phase 1Oct 1, 2009Medivation, Pfizer
NCT00954590Phase 3Oct 1, 2009Medivation, Pfizer
NCT00912288Phase 3Sep 1, 2009Medivation, Pfizer
NCT00939783Phase 3Sep 1, 2009Medivation, Pfizer
NCT00931073Phase 1Jul 1, 2009Medivation, Pfizer
NCT00920946Phase 3Jul 1, 2009Medivation, Pfizer
NCT00907322Phase 1Jun 1, 2009Medivation, Pfizer
NCT00829374Phase 3Mar 1, 2009Medivation, Pfizer
NCT00838110Phase 3Feb 1, 2009Medivation, Pfizer
NCT00831532Phase 1Feb 1, 2009Medivation, Pfizer
NCT00825084Phase 1Feb 1, 2009Medivation, Pfizer
NCT00824590Phase 1Feb 1, 2009Medivation, Pfizer
NCT00827034Phase 1Feb 1, 2009Medivation, Pfizer
Showing 20 of 28 trials
Page 1 / 2

Organizations

Research & Development (5)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
MedivationFor profit261132005
PfizerFor profit211632008
Huntington Study GroupAcademic/Hospital2012006
University of RochesterAcademic/Hospital2012006
Bigespas LTDFor profit1112023
5 organizations
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