jts-653
Small moleculeexperimental
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
- Vanilloid receptorANTAGONIST
TRPV1 antagonist
Chemistry & pharmacology
Loading structure…
SMILES
Cc1ccc(N2c3cccc(C(=O)Nc4ccc(OCC(F)(F)F)nc4)c3OC[C@@H]2CO)nc1- Mol. weight
- 474.44 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5314399 ↗
- ChEMBLCHEMBL3545228 ↗
Also known as
- 3-(hydroxymethyl)-4-(5-methylpyridin-2-yl)-n-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-3,4-dihydro-2h-benzo(b)(1,4)oxazine-8-carboxamide
- jts-653
- jts-653