ferrous citrate

Small moleculeexperimental

Ferrous citrate, also known as iron(II) citrate or iron(2+) citrate, describes coordination complexes containing citrate anions with Fe2+ formed in aqueous solution. Although a number of complexes are possible (or even likely), only one complex has been crystallized. That complex is the coordination polymer with the formula [Fe(H2O)6]2+{[Fe(C6H5O7)(H2O)]−}2.2H2O, where C6H5O73- is HOC(CH2CO2−)2(CO2−, i.e., the triple conjugate base of citric acid wherein the three carboxylic acid groups are ionized. Ferrous citrates are all paramagnetic, reflecting the weak crystal field of the carboxylate ligands. — Wikipedia

Clinical trial activity

2 trials · 5 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
2
Phase 3
0
Phase 4
0

Earliest trial started Sep 6, 2019 (NCT04020653)

Timeline

2010s

  1. Jan 1, 2019

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

  • IronSupplementation

    Iron supplementation

Chemistry & pharmacology

Mol. weight
545.73 g/mol
Chirality
Achiral Molecule
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Discontinued

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • fe(ii) citrate
  • ferrous citrate
  • ferrous citrate
  • ferrous citrate
  • monoferrous acid citrate

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07027670Phase 2Feb 1, 2021Emerald Clinical Inc., SBI Pharmaceuticals Co, Ltd., University of Oxford
NCT04020653Phase 2Sep 6, 2019Neopharma, Parexel
Showing 2 of 2 trials
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Organizations

Research & Development (5)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Emerald Clinical Inc.Academic/Hospital1012021
NeopharmaFor profit1112019
ParexelFor profit1012019
SBI Pharmaceuticals Co, Ltd.For profit1012021
University of OxfordAcademic/Hospital1112021
5 organizations
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