ferric pyrophosphate citrate

Trade name: Triferic

Small moleculeapproved

Approved

Jan 23, 2015

Iron(III) pyrophosphate is an inorganic chemical compound with the formula Fe4(P2O7)3. — Wikipedia

Clinical trial activity

30 trials · 20 clinical orgs · 1 marketing orgs

Phase 1
11
Phase 2
13
Phase 3
4
Phase 4
1

Earliest trial started Oct 1, 2003 (NCT00867867)

Timeline

2000s

  1. Jan 1, 2003

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2007

    Rockwell Medical Inc — Earliest Phase 2 Sponsor(trial)

2010s

  1. Jan 1, 2011

    Rockwell Medical Inc — Earliest Phase 3 Sponsor(trial)

  2. Jan 23, 2015

    Rockwell Medical Inc — Earliest FDA Approval

  3. Jan 23, 2015

    Rockwell Medical Inc — NDA Secondary Org

  4. Jan 23, 2015

    Rockwell Medical Inc — NDA Organization

Indications

Mechanism of action

Approval history

  • approvedJan 23, 2015

Chemistry & pharmacology

Mol. weight
1321.57 g/mol
Chirality
Achiral Molecule
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Discontinued

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • actiferol fe
  • ferric pyrophosphate
  • ferric pyrophosphate
  • ferric pyrophosphate
  • ferric pyrophosphate
  • ferric pyrophosphate
  • ferric pyrophosphate citrate
  • ferric pyrophosphate citrate
  • ferric pyrophosphate citrate
  • ferric pyrophosphate citrate
  • ferric pyrophosphate soluble
  • iron(iii) pyrophosphate
  • iron(iii) pyrophosphate
  • iron pyrophosphate
  • iron pyrophosphate
  • iron pyrophosphate
  • sodium ferricitropyrophosphate
  • soluble ferric pyrophosphate
  • soluble ferric pyrophosphate
  • soluble ferric pyrophosphate
  • sunactive fe
  • triferic

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05985070N/AJul 17, 2023Liaquat University of Medical & Health Sciences
NCT05110768Phase 2Nov 30, 2021Rockwell Medical Inc
NCT04689932Phase 4Apr 19, 2021Rockwell Medical Inc
NCT04409132Phase 1/Phase 2 (Phase 2)Jun 1, 2020Rockwell Medical Inc
NCT04239391Phase 3Jan 30, 2020Rockwell Medical Inc
NCT04042324Phase 1/Phase 2 (Phase 2)Aug 20, 2019Rockwell Medical Inc
NCT03762148N/AMar 12, 2019Antistress AG, Swiss Federal Institute of Technology, University of Zurich
NCT03303144Phase 1/Phase 2 (Phase 2)Oct 1, 2017Orlando Clinical Research Center, Rockwell Medical Inc
NCT02909153Phase 1Jan 1, 2017Rockwell Medical Inc
NCT03586245N/AOct 28, 2016Iowa State University
NCT02905981Phase 2Oct 1, 2016Rockwell Medical Inc
NCT02714075N/AApr 30, 2016Swiss Federal Institute of Technology, University for Development Studies, Tamale, Ghana
NCT02767128Phase 1Apr 1, 2016Rockwell Medical Inc
NCT02739100Phase 1Apr 1, 2016Rockwell Medical Inc
NCT03771092N/ANov 2, 2015University of Palermo
NCT02595437Phase 1/Phase 2 (Phase 2)Nov 1, 2015Rockwell Medical Inc
NCT02636049Phase 1Oct 1, 2015Rockwell Medical Inc
NCT02255942N/AApr 30, 2015PATH, Swiss Federal Institute of Technology
NCT01991626N/ASep 1, 2013DSM, Swiss Federal Institute of Technology, University of Zurich
NCT01894906Phase 1/Phase 2 (Phase 2)Jul 1, 2013Rockwell Medical Inc
Showing 20 of 30 trials
Page 1 / 2

Organizations

Research & Development (20)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Rockwell Medical IncFor profit201952007
Swiss Federal Institute of TechnologyAcademic/Hospital5512012
University of ZurichAcademic/Hospital2012013
Antistress AGFor profit1012019
Charles Drew UniversityAcademic/Hospital1112008
DSMFor profit1012013
International Center for Diarrheal Disease ResearchAcademic/Hospital1112003
Iowa State UniversityAcademic/Hospital1112016
Liaquat University of Medical & Health SciencesAcademic/Hospital1112023
National Institutes of Health (NIH)Government1012008
Nutrition Third World, BelgiumAcademic/Hospital1012003
Orlando Clinical Research CenterFor profit1012017
PATHAcademic/Hospital1012015
Quadram InstituteAcademic/Hospital1112007
Swiss National Science FoundationGovernment1012012
The Coca-Cola CompanyFor profit1012007
University for Development Studies, Tamale, GhanaAcademic/Hospital1012016
University of BaselAcademic/Hospital1012012
University of East AngliaAcademic/Hospital1012007
University of PalermoAcademic/Hospital1112015
20 organizations
Page 1 / 1

Marketing (2)

OrganizationOrg typeRelationshipDate
Rockwell Medical IncFor profitNDA2Jan 23, 2015
Rockwell Medical IncFor profitNDAJan 23, 2015