elocalcitol
Small moleculeexperimental
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
- Vitamin D receptorAGONIST
VDR agonist
Development terminated due to unmet primary end points for treatment of OAB in Ph2b trial
Chemistry & pharmacology
Loading structure…
SMILES
C=C1/C(=C\C=C2/CCC[C@]3(C)C([C@@H](C)C/C=C/C(O)(CC)CC)=CCC23)C[C@@H](O)C[C@@H]1O- Mol. weight
- 440.67 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3545094 ↗
Also known as
- 1alpha-fluoro-25-hydroxy-16,23e-diene-26,27-bishomo-20-epi-cholecalciferol
- bxl628
- bxl-628
- bxl-628
- bxl-628
- elocalcitol
- elocalcitol
- elocalcitol
- ro 26-9228
- ro-26-9228
- ro-26-9228
- ro-26-9228