l-alanyl-l-glutamine
Small moleculeexperimental
Clinical trial activity
14 trials · 16 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
8
Phase 3
5
Phase 4
4
Earliest trial started Jun 1, 2001 (NCT00558155)
Timeline
Indications
Approved for
Studied for
- Acute Kidney Injury · Phase 3
- Brain Injuries, Traumatic · Phase 4
- Cardiopulmonary Bypass · Phase 3
- Clostridium Infections · Phase 2
- Coma · Phase 4
- Coronary Artery Bypass · Phase 3
- Coronary Artery Disease · Phase 3
- Diarrhea · Phase 3
- General Surgery · Phase 4
- Intestinal Neoplasms · Phase 4
- Kidney Failure, Chronic · Phase 1/Phase 2
- Malnutrition · Phase 3
- Mental Disorders · Phase 3
- Pancreatic Neoplasms · Phase 4
- Stomach Neoplasms · Phase 4
- Thoracic Surgery · Phase 3
Mechanism of action
- Unspecified targetSupplementation
supplementation
Chemistry & pharmacology
Loading structure…
SMILES
C[C@H](N)C(=O)N[C@@H](CCC(N)=O)C(=O)O- Mol. weight
- 217.22 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3707366 ↗
Also known as
- ala-gln
- alanylglutamine
- alanylglutamine
- alanylglutamine
- alanyl glutamine
- alanyl glutamine
- alanyl glutamine
- alanyl glutamine
- alanyl glutamine
- alanyl-glutamine
- alanyl-glutamine
- alanyl-glutamine
- alanyl-glutamine
- alanylglutamine, (d-glu)-isomer
- dipeptamin
- dipeptiven
- dipeptiven
- dipeptiven
- l-ala-l-gln
- l-alanyl-l-glutamine
- n(2)-l-alanyl-l-glutamine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04560309 | Phase 3 | Oct 31, 2020 | University of Indonesia |
| NCT06065566 | N/A | Feb 4, 2020 | Instituto Mexicano del Seguro Social |
| NCT04019184 | Phase 3 | Jul 31, 2019 | Fresenius, University of Munster |
| NCT02053350 | Phase 2 | Apr 1, 2015 | University of Virginia |
| NCT04250467 | Phase 1/Phase 2 (Phase 2) | Feb 15, 2015 | Temple Therapeutics BV |
| NCT01832636 | Phase 3 | Oct 1, 2013 | Federal University of Ceara, University of Cincinnati |
| NCT01353638 | Phase 1/Phase 2 (Phase 2) | Apr 1, 2011 | Medical University of Vienna, University of Vienna |
| NCT00647036 | Phase 4 | Jul 1, 2008 | National Institutes of Health (NIH) |
| NCT01704664 | N/A | Mar 1, 2007 | Medical University of Bialystok |
| NCT02130674 | Phase 4 | Jan 1, 2005 | Fresenius, Swiss National Science Foundation, University of Zurich |
| NCT00338221 | Phase 3 | Aug 1, 2004 | National Institute of Allergy and Infectious Diseases (NIAID), University of Virginia |
| NCT00133562 | Phase 3 | Aug 1, 2004 | National Institute of Allergy and Infectious Diseases (NIAID), University of Virginia |
| NCT00732849 | Phase 4 | Jun 1, 2002 | Jagiellonian University |
| NCT00558155 | Phase 4 | Jun 1, 2001 | Jagiellonian University |
Showing 14 of 14 trials
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Organizations
Research & Development (16)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Virginia | Academic/Hospital | 3 | 3 | 2 | 2004 |
| Fresenius | For profit | 2 | 0 | 2 | 2005 |
| Jagiellonian University | Academic/Hospital | 2 | 2 | 1 | 2001 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 2 | 0 | 1 | 2004 |
| Federal University of Ceara | Academic/Hospital | 1 | 0 | 1 | 2013 |
| Instituto Mexicano del Seguro Social | Government | 1 | 1 | 1 | 2020 |
| Medical University of Bialystok | Academic/Hospital | 1 | 1 | 1 | 2007 |
| Medical University of Vienna | Academic/Hospital | 1 | 1 | 1 | 2011 |
| National Institutes of Health (NIH) | Government | 1 | 1 | 1 | 2008 |
| Swiss National Science Foundation | Government | 1 | 0 | 1 | 2005 |
| Temple Therapeutics BV | For profit | 1 | 1 | 1 | 2015 |
| University of Cincinnati | Academic/Hospital | 1 | 1 | 1 | 2013 |
| University of Indonesia | Academic/Hospital | 1 | 1 | 1 | 2020 |
| University of Munster | Academic/Hospital | 1 | 1 | 1 | 2019 |
| University of Vienna | Academic/Hospital | 1 | 0 | 1 | 2011 |
| University of Zurich | Academic/Hospital | 1 | 1 | 1 | 2005 |
16 organizations
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