rantudil
Small moleculeexperimental
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
- CyclooxygenaseINHIBITOR
Cyclooxygenase inhibitor
Non-steroidal anti-inflammatory drug. Acemetacin works by blocking the effect of natural substances called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.
It has modest selectivity for COX-1.
Chemistry & pharmacology
Loading structure…
SMILES
COc1ccc2c(c1)c(CC(=O)OCC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1- Mol. weight
- 415.83 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL189171 ↗
Also known as
- 1h-indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, carboxymethyl ester
- acemet
- acemetacin
- acemetacin
- acemetacin
- acemetacin
- acemetacin
- acemetacin
- acemetacin heumann
- acemetacin intermuti
- acemetacin monohydrate
- acemetacin sodium
- acemetacin stada
- acemetacin von ct
- acemetadoc
- acemethacin
- acemethazine
- acephlogont
- azeat
- azupharma brand of acemetacin
- bayer brand of acemetacin
- ct-arzneimittel brand of acemetacin
- docpharm brand of acemetacin
- emflex
- emflex
- emflex
- espledol
- europharma brand of acemetacin
- fher brand of acemetacin
- heumann brand of acemetacin
- indomethacin carboxymethyl ester
- intermuti brand of acemetacin
- merck brand of acemetacin
- mibe brand of acemetacin
- oldan
- rantodil
- rantudil
- rantudil
- stada brand of acemetacin
- tropon brand of acemetacin
- tvx 1322