suprofen
Trade name: Profenal
Small moleculewithdrawn
Approved
Dec 23, 1988
Suprafen is a dual inhibitor of COX-1 and COX-2, which was used for the inhibition of intraoperative miosis. Suprafen was marketed under the name Profenal, however, it is no longer available in the USA. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 2 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
Indications
Approved for
Mechanism of action
- CyclooxygenaseINHIBITOR
Cyclooxygenase inhibitor
Approval history
- withdrawnDec 23, 1988
Chemistry & pharmacology
Loading structure…
SMILES
CC(C(O)=O)C1=CC=C(C=C1)C(=O)C2=CC=CS2- Mol. weight
- 260.308 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
Oral
No
Parenteral
No
Topical
Yes
Sources
- WikipediaSuprofen ↗
- NCATS988GU2F9PE ↗
- ChEMBLCHEMBL956 ↗
Also known as
- 2-(4-(2-thenoyl)phenyl)propionsaeure
- 2-(4-(2-thenoyl)phenyl)propionsaeure
- 2-[4-(thiophene-2-carbonyl)-phenyl]-propionic acid
- 2-[4-(thiophene-2-carbonyl)-phenyl]-propionic acid
- (+-)-2-(p-(2-thenoyl)phenyl)propionic acid
- (+-)-2-(p-(2-thenoyl)phenyl)propionic acid
- 4-(2-thenoyl)hydratropsaeure
- 4-(2-thenoyl)hydratropsaeure
- alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid
- alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid
- masterfen
- p-2-thenoylhydratropic acid
- p-2-thenoylhydratropic acid
- profenal
- profenal
- profenal
- profenol
- r-25061
- r-25061
- racemic suprofen
- suprofen
- suprofen
- suprofen
- suprofen
- suprofen
- suprofen
- suprofen
- suprofen
- suprofen
- suprofen
- (+/-)-suprofen
- suprofene
- suprofene
- suprofène
- suprofène
- suprofeno
- suprofeno
- suprofen rs
- suprofenum
- suprofenum
- sutoprofen
- sutoprofen
- sutoprofen
- sutoprofen