sodium tetradecyl sulfate
Trade name: Sotradecol
Small moleculeapproved
Approved
Aug 13, 1946
Sodium tetradecyl sulfate (STS), also known by its INCI name, sodium myristyl sulfate, is a common anionic surfactant. The compound consists of the sodium salt of the micelle-forming sulfate ester of tetradecanol. It is a white, water-soluble solid of low toxicity with many practical uses. — Wikipedia
Clinical trial activity
11 trials · 14 clinical orgs · 5 marketing orgs
Phase 1
1
Phase 2
3
Phase 3
1
Phase 4
3
Earliest trial started Mar 31, 2010 (NCT03363633)
Timeline
1940s
- Aug 13, 1946
AH Robins — Earliest FDA Approval
- Aug 13, 1946
Elkins Sinn — NDA Secondary Org
- Aug 13, 1946
AH Robins — NDA Organization
2000s
- Nov 12, 2004
Mylan — Marketing Organization
2010s
- Jan 1, 2017
Earliest Phase 2 Sponsor(trial)
- Jan 1, 2018
Earliest Phase 3 Sponsor(trial)
- Dec 9, 2019
Hikma — Marketing Organization
- Dec 9, 2019
Custopharm Inc — Marketing Organization
2020s
- Jan 1, 2020
Earliest Phase 1 Sponsor(trial)
Indications
Approved for
Mechanism of action
- Lipid bilayerDISRUPTING AGENT
Lipid bilayer disrupting agent
Approval history
- approvedPriority reviewAug 13, 1946
Chemistry & pharmacology
Loading structure…
SMILES
CCCCC(CC)CCC(CC(C)C)OS(=O)(=O)[O-].[Na+]- Mol. weight
- 316.44 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
- Delivery
- Parenteral
- Availability
- Prescription Only
Oral
No
Parenteral
Yes
Topical
No
Sources
- WikipediaSodium tetradecyl sulfate ↗
- ChEMBLCHEMBL1200354 ↗
Also known as
- 7-ethyl-2-methyl-4-undecanol sulfate sodium salt
- 7-ethyl-2-methyl-4-undecanol sulfate sodium salt
- 7-ethyl-2-methyl-4-undecanolsulfate, sodium salt
- 7-ethyl-2-methyl-4-undecanolsulfate, sodium salt
- fibrovein
- fibro-vein
- natrii tetradecylis sulfa
- natrii tetradecylis sulfa
- sodium 2-methyl-7-ethylundecanol-4-sulfate
- sodium 2-methyl-7-ethylundecanol-4-sulfate
- sodium 7-ethyl-2-methyl-4-undecanol sulfate
- sodium 7-ethyl-2-methyl-4-undecanol sulfate
- sodium tetradecylsulfate
- sodium tetradecylsulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulfate
- sodium tetradecyl sulphate
- sodium tetradecyl sulphate
- sodium tetradecyl sulphate
- sodium tetradecyl sulphate
- sotradecol
- sotradecol
- sotradecol
- sotradecol
- s.t.d.
- s.t.d.
- sts
- sts
- tetradecilsulfato sodico
- tetradecilsulfato sodico
- tetradecyl sodium sulfate
- tetradecyl sodium sulfate
- tetradecyl sodium sulphate
- tetradecyl sodium sulphate
- tetradecyl sulfate de sodium
- tetradecyl sulfate de sodium
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05597995 | Phase 2 | Nov 1, 2022 | Goldman, Butterwick, Fitzpatrick and Groff |
| NCT04655417 | Early Phase 1 (Phase 1) | Feb 21, 2020 | Pakistan Army |
| NCT06106971 | Phase 3 | Jun 28, 2018 | Kaohsiung Medical University |
| NCT03311269 | Phase 2 | Sep 22, 2017 | University of Washington, Vascular Insights LLC |
| NCT02557542 | N/A | Oct 1, 2015 | University of London |
| NCT02627846 | Phase 4 | Jun 1, 2015 | University of Hull |
| NCT02010437 | Phase 4 | Jan 1, 2014 | University of Hull |
| NCT06192472 | N/A | Apr 30, 2013 | University of Surrey |
| NCT01347294 | Phase 4 | Aug 1, 2011 | Osaka University, University of Oslo |
| NCT01408732 | N/A | Feb 1, 2011 | American Rhinologic Society, University of Minnesota |
| NCT03363633 | N/A | Mar 31, 2010 | American College of Phlebology, University of Pittsburgh |
Showing 11 of 11 trials
Page 1 / 1
Organizations
Research & Development (14)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Hull | Academic/Hospital | 2 | 2 | 1 | 2014 |
| American College of Phlebology | Academic/Hospital | 1 | 0 | 1 | 2010 |
| American Rhinologic Society | Academic/Hospital | 1 | 0 | 1 | 2011 |
| Goldman, Butterwick, Fitzpatrick and Groff | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Kaohsiung Medical University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Osaka University | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Pakistan Army | Government | 1 | 1 | 1 | 2020 |
| University of London | Academic/Hospital | 1 | 1 | 1 | 2015 |
| University of Minnesota | Academic/Hospital | 1 | 1 | 1 | 2011 |
| University of Oslo | Academic/Hospital | 1 | 0 | 1 | 2011 |
| University of Pittsburgh | Academic/Hospital | 1 | 1 | 1 | 2010 |
| University of Surrey | Academic/Hospital | 1 | 1 | 1 | 2013 |
| University of Washington | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Vascular Insights LLC | For profit | 1 | 1 | 1 | 2017 |
14 organizations
Page 1 / 1
Marketing (5)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| AH Robins | For profit | NDA | Aug 13, 1946 |
| Custopharm Inc | For profit | MKTG | Dec 9, 2019 |
| Elkins Sinn | For profit | NDA2 | Aug 13, 1946 |
| Hikma | For profit | MKTG | Dec 9, 2019 |
| Mylan | For profit | MKTG | Nov 12, 2004 |