medrysone
Trade name: hms
Small moleculeapproved
Approved
Nov 28, 1969
Medrysone is a synthetic glucocorticoid used to to treat inflammatory eye diseases such as allergic conjunctivitis, vernal conjunctivitis, and episcleritis. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 1 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
Indications
Mechanism of action
- Glucocorticoid receptorAGONIST
NR3C1 agonist
Approval history
- approvedNov 28, 1969
Chemistry & pharmacology
Loading structure…
SMILES
C[C@H]1C[C@H]2[C@@H]3CC[C@H](C(C)=O)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)CCC(=O)C=C14- Mol. weight
- 344.4877 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Discontinued
Oral
No
Parenteral
No
Topical
Yes
Sources
- WikipediaMedrysone ↗
- NCATSD2UFC189XF ↗
- ChEMBLCHEMBL1201173 ↗
Also known as
- 11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione
- 11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione
- 11-hydroxy-6-methylprogesterone
- hms
- hms
- hms
- hms liquifilm
- hms suspension
- hydroxymesterone
- hydroxymesterone
- hydroxymesterone
- medrifar
- medrocort
- medrysone
- medrysone
- medrysone
- medrysone
- medrysone
- medrysone
- medrysone
- medrysone
- medrysone
- medrysone
- medrysone
- u-8471
- u-8471