drostanolone
Trade name: drolban
Dromostanolone Propionate (known by the brand names Masteron and Drolban) was invented by Syntex in 1959. About 10 years later it was released on the American market by Lilly as brand name Drolban. The drug was first approved in the USA for use as a treatment of female breast cancer. However, the profile of side-effects included pronouncement of male characteristics in women and when more effective breast cancer treatments came to market drostanolone was gradually phased out. No longer used clinically dromostanolone propionate became very popular in the bodybuilding community. Today dromostanolone propionate remains on the list of approved medications, but it is not being manufactured or sold by pharmaceutical companies. It is still produced illegally by underground labs for use in the bodybuilding community. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 1 marketing orgs
Timeline
Indications
Approved for
Mechanism of action
- Androgen ReceptorAGONIST
AR agonist
Approval history
- approved—
Chemistry & pharmacology
SMILES
C[C@@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@H]23)CC1=O- Mol. weight
- 304.4669 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Parenteral
- Availability
- Discontinued
Oral
No
Parenteral
Yes
Topical
No
Sources
- WikipediaDrostanolone ↗
- NCATS7DR7H00HDT ↗
- ChEMBLCHEMBL1201048 ↗
Also known as
- 17 beta-hydroxy-2 alpha-methyl-5 alpha-androstan-3-one
- 17beta-hydroxy-2alpha-methyl-5alpha-androstan-3-one
- 17beta-hydroxy-2alpha-methyl-5alpha-androstan-3-one
- 2alpha-methyldihydrotestosterone
- 2alpha-methyldihydrotestosterone
- 2 alpha-methyldihydrotestosterone propionate
- 32379
- dihydro-2alpha-methyltestosterone
- dihydro-2alpha-methyltestosterone
- drolban
- drolban
- drolban
- drolban
- dromostanolone
- dromostanolone
- dromostanolone
- dromostanolone
- dromostanolone, (5alpha,17beta)-isomer
- dromostanolone propionate
- dromostanolone propionate
- dromostanolone propionate
- dromostanolone propionate
- dromostanolone propionate
- dromostanolone propionate
- drostanolon
- drostanolona
- drostanolona
- drostanolone
- drostanolone
- drostanolone
- drostanolone
- drostanolone
- drostanolone propionate
- drostanolone propionate
- drostanolone propionate
- drostanolone propionate
- drostanolone propionate
- drostanolonum
- drostanolonum
- emdisterone
- masteril
- masteril
- masteril
- masterone
- medrosteron
- medrosteron
- medrotestron
- medrotestron
- medrotestron
- medrotestron
- medrotestron
- medrotestrone propanoate
- medrotestrone propionate
- medrotestron propionate
- methalone
- metholone
- metholone
- metholone
- nsc 12198
- nsc-12198
- permastril
- prometholone
- prometholone
Organizations
Marketing (1)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Eli Lilly | For profit | NDA | Jun 1, 1961 |