acetophenazine
Trade name: tindal
Small moleculeapproved
Approved
Apr 5, 1961
Acetophenazine (Tindal) is an antipsychotic drug of moderate-potency. Used in the treatment of disorganized and psychotic thinking. Acetophenazine (Tindal) is also used to help treat false perceptions (e.g. hallucinations or delusions). Acetophenazine acts as an antagonist of dopaminergic D2 receptors in the brain. Acetophenazine exhibited modest androgen receptor binding and antiandrogen activity. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 1 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
Indications
Approved for
Mechanism of action
- Dopamine D2 receptorANTAGONIST
DRD2 antagonist
Approval history
- approvedApr 5, 1961
Chemistry & pharmacology
Loading structure…
SMILES
CC(=O)c1ccc2c(c1)N(CCCN1CCN(CCO)CC1)c1ccccc1S2- Mol. weight
- 411.57 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Oral
- Availability
- Discontinued
Oral
Yes
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL1085 ↗
- WikipediaAcetophenazine ↗
- NCATS8620H6K4QH ↗
- ChEMBLCHEMBL2360079 ↗
Also known as
- acephenazine dimaleate
- acephenazine dimaleate
- acetofenazine
- acetofenazine
- acetofenazine
- acetofenazine
- acetofenazine
- acetofenazine maleate
- acetophenazine
- acetophenazine
- acetophenazine
- acetophenazine
- acetophenazine
- acetophenazine
- acetophenazine
- acetophenazine
- acetophenazine
- acetophenazine, ion (1+)
- acetophenazine maleate
- acetophenazine maleate
- acetophenazine maleate
- acetophenazine maleate
- acetophenazine maleate
- acetophenazine, (z)-2-maleate (1:2) salt
- sch-6673
- sch-6673
- tindal
- tindal
- tindal
- tindal
- tindal maleate