antigen pulsed dendritic cells
Vaccineexperimental
Clinical trial activity
15 trials · 27 clinical orgs · 0 marketing orgs
Phase 1
6
Phase 2
9
Phase 3
3
Phase 4
0
Earliest trial started Mar 1, 2005 (NCT00834002)
Timeline
Indications
Studied for
- Antigens, Neoplasm · Phase 2
- Breast Neoplasms · Phase 2
- Breast Neoplasms, Male · Early Phase 1
- Carcinoma, Hepatocellular · Phase 2
- Colorectal Neoplasms · Phase 3
- Diabetes Mellitus, Type 2 · Phase 3
- Diffuse Intrinsic Pontine Glioma · Phase 1/Phase 2
- Esophageal Neoplasms · Phase 2
- Fallopian Tube Neoplasms · Phase 1/Phase 2
- Glioblastoma · Phase 2/Phase 3
- Glioma · Phase 1/Phase 2
- Hamartoma · Phase 1/Phase 2
- HLA-A2 Antigen · Phase 2
- Immune Checkpoint Inhibitors · Phase 2
- Leukemia, Myeloid, Acute · Phase 1
- Liver Neoplasms · Phase 2
- Melanoma · Phase 2
- Neoplasm Metastasis · Phase 2
- Ovarian Neoplasms · Phase 1/Phase 2
- Periodontal Diseases · Phase 3
Mechanism of action
- Tumor antigensImmunity, active
Tumor antigens immunity, active
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- alpha-type-1 dendritic cell-based vaccines
- alpha-type-1-polarized dendritic cell
- antigen-loaded cultured dendritic cells
- antigen pulsed dendritic cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06675201 | Phase 2 | Oct 1, 2024 | Sichuan University |
| NCT05749627 | N/A | Apr 1, 2023 | Nanchang University |
| NCT05539365 | Phase 2 | Dec 7, 2022 | State University of New York, Buffalo |
| NCT05378464 | Phase 1 | May 31, 2022 | University of South Florida, Vaccinex Inc. |
| NCT04911621 | Phase 1/Phase 2 (Phase 2) | Sep 10, 2021 | Kom Op Tegen Kanker, Olivia Hendrickx research Fund vzw, Stichting Semmy, University of Antwerp |
| NCT04912765 | Phase 2 | Apr 15, 2021 | Bristol-Myers Squibb, Government of Singapore |
| NCT04093323 | Phase 2 | Oct 1, 2019 | National Cancer Institute (NCI), State University of New York, Buffalo |
| NCT03735589 | Phase 1/Phase 2 (Phase 2) | Jun 15, 2019 | National Cancer Institute (NCI), State University of New York, Buffalo |
| NCT03548571 | Phase 2/Phase 3 (Phase 3) | Apr 26, 2018 | University of Oslo |
| NCT03387553 | Early Phase 1 (Phase 1) | Apr 6, 2018 | Department of Defense, University of South Florida |
| NCT02615574 | Phase 2 | Mar 1, 2016 | University of Pittsburgh |
| NCT02503150 | Phase 3 | Jul 1, 2015 | Changhai Hospital, Chinese Academy of Medical Sciences, First People's Hospital of Hangzhou, Fudan University, Haixin Biotechnology Co. Ltd, Jiao Tong University, Peking University, People's Liberation Army of China, Second Military Medical University, Zhejiang University |
| NCT01595594 | Phase 3 | Mar 1, 2010 | Fundação de Amparo à Pesquisa do Estado de São Paulo, University of Sao Paulo |
| NCT00558051 | Phase 1 | Jan 1, 2008 | University of Pittsburgh |
| NCT00834002 | Phase 1 | Mar 1, 2005 | University of Antwerp |
Showing 15 of 15 trials
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Organizations
Research & Development (27)
27 organizations
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