adh-1

Small moleculeexperimental

Clinical trial activity

6 trials · 5 clinical orgs · 0 marketing orgs

Phase 1
5
Phase 2
4
Phase 3
0
Phase 4
0

Earliest trial started Jun 1, 2005 (NCT00265057)

Timeline

2000s

  1. Jan 1, 2005

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2005

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O
Mol. weight
570.7 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • adh -1
  • adh -1
  • adh-1
  • adh-1
  • adh-1

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT01825603Phase 1Apr 1, 2013Fennec Pharma, National Cancer Institute (NCI), University of Nebraska
NCT00421811Phase 1/Phase 2 (Phase 2)Apr 1, 2007Duke University, Fennec Pharma
NCT00390676Phase 1Nov 1, 2006Fennec Pharma, US Oncology
NCT00264433Phase 2Dec 12, 2005Fennec Pharma
NCT00225550Phase 1/Phase 2 (Phase 2)Sep 22, 2005Fennec Pharma
NCT00265057Phase 1/Phase 2 (Phase 2)Jun 1, 2005Fennec Pharma
Showing 6 of 6 trials
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Organizations

Research & Development (5)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Fennec PharmaFor profit6522005
Duke UniversityAcademic/Hospital1012007
National Cancer Institute (NCI)Government1012013
University of NebraskaAcademic/Hospital1112013
US OncologyFor profit1012006
5 organizations
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