wharton's jelly mesenchymal stem cells
Cell therapyexperimental
Clinical trial activity
45 trials · 61 clinical orgs · 0 marketing orgs
Phase 1
28
Phase 2
31
Phase 3
6
Phase 4
0
Earliest trial started Mar 1, 2015 (NCT02368587)
Timeline
Indications
Studied for
- Allogeneic Cells · Phase 1
- Allografts · Phase 1
- Amyotrophic Lateral Sclerosis · Phase 1/Phase 2
- Anterior Wall Myocardial Infarction · Phase 3
- Autistic Disorder · Phase 1
- Cardiomyopathies · Phase 2
- Cardiovascular Diseases · Phase 1/Phase 2
- Coronary Artery Disease · Phase 2
- COVID-19 · Phase 2
- Diabetes Mellitus, Type 1 · Phase 1/Phase 2
- Diabetes Mellitus, Type 2 · Phase 1/Phase 2
- Diabetic Nephropathies · Phase 1/Phase 2
- Erectile Dysfunction · Phase 1/Phase 2
- Fractures, Bone · Phase 2
- Graft vs Host Disease · Phase 1/Phase 2
- Heart Failure · Phase 3
- Inflammatory Bowel Diseases · Phase 1/Phase 2
- Influenza A virus · Phase 1
- Knee Injuries · Phase 2
- Low Back Pain · Phase 1
- Mesenchymal Stem Cell Transplantation · Phase 1/Phase 2
- Metapneumovirus · Phase 1
- Myocardial Infarction · Phase 3
- Osteoarthritis · Phase 1/Phase 2
- Osteoarthritis, Hip · Phase 1/Phase 2
- Osteoarthritis, Knee · Phase 2
- Osteoporotic Fractures · Phase 2
- Poisoning · Phase 3
- Regenerative Medicine · Phase 3
- Respiratory Distress Syndrome · Phase 1/Phase 2
- Respiratory Syncytial Virus Infections · Phase 1
- Retinal Diseases · Phase 3
- Retinitis Pigmentosa · Phase 3
- SARS-CoV-2 · Phase 1/Phase 2
- Spinal Cord Diseases · Phase 1/Phase 2
- Spinal Cord Injuries · Phase 1/Phase 2
- ST Elevation Myocardial Infarction · Phase 3
- Stem Cells · Phase 3
- Toxic Optic Neuropathy · Phase 3
- Transcranial Magnetic Stimulation · Phase 3
- Ventricular Remodeling · Phase 3
Mechanism of action
- Stem CellTissue restoration
Stem Cell tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- wharton' jelly-derived mesenchymal stem cells
- wharton's jelly mesenchymal stem cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07018739 | Phase 1/Phase 2 (Phase 2) | Jun 30, 2026 | Mahidol University, Siriraj Hospital |
| NCT06981338 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2025 | Institut Guttmann |
| NCT06608134 | Early Phase 1 (Phase 1) | Oct 1, 2024 | R3 Medical Research |
| NCT06495437 | N/A | Aug 1, 2024 | — |
| NCT06304025 | Phase 1/Phase 2 (Phase 2) | Jun 30, 2024 | Fundación Oftalmológica de Santander Clínica Carlos Ardila Lulle, Instituto Distrital de Ciencia Biotecnología e Innovacion en Salud |
| NCT06218134 | N/A | Mar 30, 2024 | Sungkyunkwan University |
| NCT06361485 | Phase 1 | Mar 25, 2024 | R3 Medical Research, R3 Stem Cell |
| NCT05855707 | Phase 1 | Sep 30, 2023 | University of Lorraine, University of Paris |
| NCT05413148 | Phase 2/Phase 3 (Phase 3) | Aug 5, 2022 | Erciyes University |
| NCT06293950 | Phase 1 | Mar 9, 2022 | University of Jordan |
| NCT04711304 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2022 | BioIntegrate, El-Amin Orthopaedic & Sports Medicine Institute |
| NCT04719793 | Early Phase 1 (Phase 1) | Jan 1, 2022 | BioIntegrate, El-Amin Orthopaedic & Sports Medicine Institute |
| NCT05054803 | Phase 1/Phase 2 (Phase 2) | Oct 31, 2021 | Academic Research Organization (ARO) - VHIR, Banc de Sang i Teixits, Institut Guttmann |
| NCT04869397 | Phase 2 | Jun 14, 2021 | McGill University |
| NCT04896853 | Phase 1 | May 18, 2021 | Karolinska Institute, NextCell Pharma, Orebro University |
| NCT05043610 | Phase 3 | Jan 1, 2021 | Cell Tech Pharmed Company, Iran, Government of Iran, Shiraz University |
| NCT04651855 | Phase 1/Phase 2 (Phase 2) | Dec 2, 2020 | Government of Poland, Polski Bank Komorek Macierzystych JSC (PBKM) |
| NCT04551456 | Phase 2 | Nov 30, 2020 | Chinese Academy of Medical Sciences, Government of China, Peking University, People's Liberation Army of China, Xijing Hospital |
| NCT04625738 | Phase 2 | Nov 6, 2020 | University of Lorraine |
| NCT04551443 | Phase 2 | Nov 1, 2020 | Chinese Academy of Medical Sciences, Government of China, Peking University, People's Liberation Army of China, Xijing Hospital |
Showing 20 of 45 trials
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Organizations
Research & Development (61)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Jordan | Academic/Hospital | 4 | 2 | 2 | 2017 |
| Ankara Universitesi Teknokent | Academic/Hospital | 3 | 3 | 1 | 2019 |
| Banc de Sang i Teixits | Academic/Hospital | 3 | 3 | 1 | 2016 |
| BioIntegrate | For profit | 3 | 3 | 2 | 2020 |
| Government of China | Government | 3 | 3 | 1 | 2015 |
| Institut Guttmann | Academic/Hospital | 3 | 1 | 1 | 2016 |
| NextCell Pharma | For profit | 3 | 3 | 2 | 2017 |
| People's Liberation Army of China | Government | 3 | 0 | 1 | 2015 |
| Al-Ahliyya Amman University | Academic/Hospital | 2 | 2 | 1 | 2017 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 2 | 0 | 1 | 2020 |
| El-Amin Orthopaedic & Sports Medicine Institute | Academic/Hospital | 2 | 0 | 2 | 2022 |
| Erciyes University | Academic/Hospital | 2 | 2 | 2 | 2019 |
| Government of Poland | Government | 2 | 0 | 2 | 2017 |
| Peking University | Academic/Hospital | 2 | 0 | 1 | 2020 |
| R3 Medical Research | For profit | 2 | 1 | 1 | 2024 |
| University of Lorraine | Academic/Hospital | 2 | 2 | 2 | 2020 |
| Xijing Hospital | Academic/Hospital | 2 | 0 | 1 | 2020 |
| Academic Research Organization (ARO) - VHIR | Academic/Hospital | 1 | 0 | 1 | 2021 |
| An-Najah National University | Academic/Hospital | 1 | 0 | 1 | 2019 |
| APHP - Hôpital Necker | Academic/Hospital | 1 | 0 | 1 | 2020 |
61 organizations
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