← Mechanisms of action
IL6R
SINGLE PROTEINHomo sapiens
Preferred name: Interleukin-6 receptor alpha subunit ChEMBL ↗
Linked proteins
Drugs acting on this target (8)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ro7200220 | Antagonist | experimental | mAb | IL6R antagonist |
| sarilumab (kevzara) | Antagonist | approved | mAb | IL6R antagonist |
| alx-0061 | Inhibitor | experimental | mAb | IL6R inhibitor |
| AMG220 | Inhibitor | experimental | Recombinant protein | IL6R inhibitor |
| bcd-089 | Inhibitor | experimental | mAb | Interleukin-6 receptor alpha subunit inhibitor |
| satralizumab (Enspryng) | Inhibitor | approved | mAb | IL6R inhibitor |
| tocilizumab (actemra) | Inhibitor | approved | mAb | IL6R inhibitor |
| zenuzolac | Inhibitor | experimental | Small molecule | IL6R inhibitor |