← Mechanisms of action
JAK2
SINGLE PROTEINHomo sapiens
Preferred name: Tyrosine-protein kinase JAK2 ChEMBL ↗
Linked proteins
Drugs acting on this target (42)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ac-430 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| ach-0137171 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| aj1-11095 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| asn002 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| at9283 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| ati-1777 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| azd-1480 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| baricitinib (olumiant) | Inhibitor | approved | Small molecule | JAK2 inhibitor |
| bms-911543 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| cee321 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| cpl409116 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| delgocitinib (Anzupgo) | Inhibitor | approved | Small molecule | JAK2 inhibitor |
| deuruxolitinib | Inhibitor | approved | Small molecule | JAK2 inhibitor |
| fedratinib (Inrebic) | Inhibitor | approved | Small molecule | JAK2 inhibitor |
| filgotinib (Jyseleca) | Inhibitor | experimental | Small molecule | Tyrosine-protein kinase JAK2 inhibitor |
| flonoltinib | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| gandotinib | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| incb052793 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| incb160058 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| jacketinib | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| jaktinib | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| kl130008 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| lestaurtinib | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| ls-104 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| ly3844583 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| max-40070 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| momelotinib (Ojjaara) | Inhibitor | approved | Small molecule | JAK2 inhibitor |
| ns-018 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| pacritinib (Vonjo) | Inhibitor | approved | Small molecule | JAK2 inhibitor |
| pf06263276 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| pro-157 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| ruxolitinib (jakafi) | Inhibitor | approved | Small molecule | JAK2 inhibitor |
| sb1578 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| syhx 1901 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| td-0903 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| td-8236 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| tg02 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| tofacitinib (xeljanz) | Inhibitor | approved | Small molecule | JAK2 inhibitor |
| tq05105 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| vr588 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| wp1066 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |
| xl019 | Inhibitor | experimental | Small molecule | JAK2 inhibitor |