← Mechanisms of action
COMT
SINGLE PROTEINHomo sapiens
Preferred name: Catechol O-methyltransferase ChEMBL ↗
Linked proteins
Drugs acting on this target (6)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| opicapone (Ongentys) | Antagonist | approved | Small molecule | COMT antagonist |
| entacapone (comtan) | Inhibitor | approved | Small molecule | COMT inhibitor |
| nebicapone | Inhibitor | experimental | Small molecule | COMT inhibitor |
| odm-104 | Inhibitor | experimental | Small molecule | COMT inhibitor |
| opicapone (Ongentys) | Inhibitor | approved | Small molecule | Catechol O-methyltransferase inhibitor |
| tolcapone (tasmar) | Inhibitor | approved | Small molecule | COMT inhibitor |