← Mechanisms of action
JAK3
SINGLE PROTEINHomo sapiens
Preferred name: Tyrosine-protein kinase JAK3 ChEMBL ↗
Linked proteins
Drugs acting on this target (27)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| at9283 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| ati-2138 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| ati-50002 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| ati-501 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| cerdulatinib | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| cs12192 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| decernotinib | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| delgocitinib (Anzupgo) | Inhibitor | approved | Small molecule | JAK3 inhibitor |
| deuruxolitinib | Inhibitor | approved | Small molecule | Tyrosine-protein kinase JAK3 inhibitor |
| dwp212525 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| filgotinib (Jyseleca) | Inhibitor | experimental | Small molecule | Tyrosine-protein kinase JAK3 inhibitor |
| Ifidancitinib | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| max-40070 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| or-101 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| ost-122 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| pf06263276 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| r-333 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| r-348 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| r348 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| r932333 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| ritlecitinib (Litfulo) | Inhibitor | approved | Small molecule | JAK3 inhibitor |
| td-5202 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| td-8236 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| tofacitinib (xeljanz) | Inhibitor | approved | Small molecule | JAK3 inhibitor |
| tricetamide | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| whi-p131 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |
| zl-82 | Inhibitor | experimental | Small molecule | JAK3 inhibitor |