← Mechanisms of action
IDH1
SINGLE PROTEINHomo sapiens
Preferred name: Isocitrate dehydrogenase [NADP] cytoplasmic ChEMBL ↗
Linked proteins
Drugs acting on this target (14)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ivosidenib (tibsovo) | Antagonist | approved | Small molecule | IDH1 |
| olutasidenib (Rezlidhia) | Antagonist | approved | Small molecule | IDH1 antagonist |
| hn2301 | Antisense inhibitor | experimental | Nucleic acid | IDH1 antisense inhibitor |
| pepidh1m | Immunity, active | experimental | Vaccine | IDH1 immunity, active |
| bay1436032 | Inhibitor | experimental | Small molecule | IDH1 inhibitor |
| ds-1001b | Inhibitor | experimental | Small molecule | IDH1 inhibitor |
| hmpl-306 | Inhibitor | experimental | Small molecule | IDH1 inhibitor |
| idh305 | Inhibitor | experimental | Small molecule | IDH1 inhibitor |
| ivosidenib (tibsovo) | Inhibitor | approved | Small molecule | Isocitrate dehydrogenase [NADP] cytoplasmic inhibitor |
| ky100001 | Inhibitor | experimental | Small molecule | IDH1 inhibitor |
| ly3410738 | Inhibitor | experimental | Small molecule | IDH1 inhibitor |
| olutasidenib (Rezlidhia) | Inhibitor | approved | Small molecule | Isocitrate dehydrogenase [NADP] cytoplasmic inhibitor |
| tqb3454 | Inhibitor | experimental | Small molecule | IDH1 inhibitor |
| Vorasidenib | Inhibitor | approved | Small molecule | IDH1 inhibitor |