← Mechanisms of action
GUCY2C
SINGLE PROTEINHomo sapiens
Preferred name: Heat-stable enterotoxin receptor ChEMBL ↗
Linked proteins
Drugs acting on this target (12)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| dolcanatide | Agonist | experimental | Peptide | Heat-stable enterotoxin receptor agonist |
| linaclotide (linzess) | Agonist | approved | Peptide | GUCY2C agonist |
| plecanatide (trulance) | Agonist | approved | Peptide | GUCY2C agonist |
| 68ga mln6907 | Binding agent | experimental | Peptide | GUCY2C binding agent |
| cvd 1208s | Immunity, active | experimental | Vaccine | GUCY2C immunity, active |
| dsccfae | Immunity, active | experimental | Vaccine | GUCY2C immunity, active |
| modified e. coli heat labile enterotoxin ltr192g | Immunity, active | experimental | Vaccine | GUCY2C immunity, active |
| gucy2c cart cells | Immunity, passive | experimental | Cell therapy | GUCY2C immunity, passive |
| im96 car-t cells | Immunity, passive | experimental | Cell therapy | GUCY2C immunity, passive |
| pf-07062119 | Inhibitor | experimental | mAb | GUCY2C inhibitor |
| TAK-164 | Inhibitor | experimental | mAb | GUCY2C inhibitor |
| venbeta6890 | Inhibitor | experimental | mAb | GUCY2C inhibitor |