← Mechanisms of action
SERPINA1
SINGLE PROTEINMus caroli
Preferred name: Alpha-1-antiproteinase ChEMBL ↗
Linked proteins
Drugs acting on this target (17)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| alpha-1 antitrypsin (Prolastin) | Antagonist | approved | Biological | SERPINA1 antagonist |
| aln-aat | Antisense inhibitor | experimental | Nucleic acid | SERPINA1 antisense inhibitor |
| wve-006 | Antisense inhibitor | experimental | Nucleic acid | SERPINA1 antisense inhibitor |
| tak-881 | Inhibitor | experimental | Recombinant protein | SERPINA1 inhibitor |
| vx-634 | Modulator | experimental | Small molecule | SERPINA1 modulator |
| vx-814 | Positive allosteric modulator | experimental | Small molecule | SERPINA1 positive allosteric modulator |
| vx-864 | Stabiliser | experimental | Small molecule | SERPINA1 stabiliser |
| aav8haat | Supplementation | experimental | Gene therapy | SERPINA1 supplementation |
| advm-043 | Supplementation | experimental | Gene therapy | SERPINA1 supplementation |
| air-001 | Supplementation | experimental | Nucleic acid | SERPINA1 supplementation |
| cj-40002 | Supplementation | experimental | Recombinant protein | SERPINA1 supplementation |
| kb408 | Supplementation | experimental | Gene therapy | SERPINA1 supplementation |
| kb707 | Supplementation | experimental | Gene therapy | SERPINA1 supplementation |
| ntla-3001 | Supplementation | experimental | Gene therapy | SERPINA1 supplementation |
| osrhaat | Supplementation | experimental | Recombinant protein | SERPINA1 supplementation |
| raav1-cb-haat | Supplementation | experimental | Gene therapy | SERPINA1 supplementation |
| vx-668 | Supplementation | experimental | Recombinant protein | SERPINA1 supplementation |