← Mechanisms of action
PRMT5
SINGLE PROTEINHomo sapiens
Preferred name: Protein arginine N-methyltransferase 5 ChEMBL ↗
Linked proteins
Drugs acting on this target (25)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| mrtx1719 | Antagonist | experimental | Small molecule | PRMT5 |
| scr-6920 | Antagonist | experimental | Small molecule | PRMT5 |
| skl27969 | Antagonist | experimental | Small molecule | PRMT5 |
| tng908 | Antagonist | experimental | Small molecule | PRMT5 |
| azd3470 | Immunity, passive | experimental | Cell therapy | PRMT5 immunity, passive |
| absk131 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| amg 193 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| bay 3713372 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| bgb-58067 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| cts3497 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| dc50292a | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| gh56 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| gsk3326595 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| hrs-6719 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| hsk41959 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| ide892 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| jnj-64619178 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| pep08 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| pf-06939999 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| prt543 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| prt811 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| sh3765 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| syhx2001 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| tng456 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |
| tng462 | Inhibitor | experimental | Small molecule | PRMT5 inhibitor |