← Mechanisms of action
NLRP3
SINGLE PROTEINHomo sapiens
Preferred name: NACHT, LRR and PYD domains-containing protein 3 ChEMBL ↗
Linked proteins
Drugs acting on this target (21)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| inzomelid | Activator | experimental | Small molecule | NLRP3 activator |
| aci-19764 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| bms-986299 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| Dapansutrile | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| dfv890 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| hl-400 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| izd334 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| jt002 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| jte-162 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| nnc6022-0001 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| nt-0796 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| ro7486967 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| rrx-001 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| su-huang | Inhibitor | experimental | Botanical | NLRP3 inhibitor |
| Taurodeoxycholate (Nusepin) | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| usnoflast | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| vent-02 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| vtx2735 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| vtx3232 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| ya-101 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |
| zyil1 | Inhibitor | experimental | Small molecule | NLRP3 inhibitor |