← Mechanisms of action
PAH
SINGLE PROTEINHomo sapiens
Preferred name: Phenylalanine-4-hydroxylase ChEMBL ↗
Linked proteins
Drugs acting on this target (9)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| sapropterin (kuvan) | Activator | approved | Small molecule | PAH activator |
| tetrahydrobiopterin | Activator | experimental | Small molecule | PAH activator |
| sapropterin (kuvan) | Agonist | approved | Small molecule | PAH agonist |
| sar444836 | Agonist | experimental | Small molecule | PAH agonist |
| ag-181 | Stabiliser | experimental | Small molecule | PAH stabiliser |
| bmn 307 | Supplementation | experimental | Gene therapy | PAH supplementation |
| hmi-102 | Supplementation | experimental | Gene therapy | PAH supplementation |
| hmi-103 | Supplementation | experimental | Gene therapy | PAH supplementation |
| nggt002 | Supplementation | experimental | Gene therapy | PAH supplementation |