← Mechanisms of action
SNCA
SINGLE PROTEINHomo sapiens
Preferred name: Alpha-synuclein ChEMBL ↗
Linked proteins
Drugs acting on this target (31)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| aln-snca | Antisense inhibitor | experimental | Nucleic acid | SNCA antisense inhibitor |
| anle138b | Antisense inhibitor | experimental | Nucleic acid | SNCA antisense inhibitor |
| biib101 | Antisense inhibitor | experimental | Nucleic acid | SNCA antisense inhibitor |
| [18f]mni-1216 | Binding agent | experimental | Small molecule | SNCA binding agent |
| 11c-m503 pet | Binding agent | experimental | Small molecule | SNCA binding agent |
| prasinezumab | Binding agent | experimental | mAb | Alpha-synuclein binding agent |
| affitope pd01a | Immunity, active | experimental | Vaccine | SNCA immunity, active |
| affitope pd03a | Immunity, active | experimental | Vaccine | SNCA immunity, active |
| ub-312 | Immunity, active | experimental | Vaccine | SNCA immunity, active |
| abbv-0805 | Inhibitor | experimental | mAb | SNCA inhibitor |
| abl301 | Inhibitor | experimental | mAb | SNCA inhibitor |
| aci-15916 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| ath434 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| biib054 | Inhibitor | experimental | mAb | SNCA inhibitor |
| Emrusolmin | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| ent-01 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| lu af82422 | Inhibitor | experimental | mAb | SNCA inhibitor |
| ly3962681 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| medi1341 | Inhibitor | experimental | mAb | SNCA inhibitor |
| mt101-5 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| npt520-34 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| prasinezumab | Inhibitor | experimental | mAb | SNCA inhibitor |
| prx002 | Inhibitor | experimental | mAb | SNCA inhibitor |
| rdc5 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| rld2104 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| ucb-2897 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| ucb0599 | Inhibitor | experimental | Small molecule | SNCA inhibitor |
| ucb7853 | Inhibitor | experimental | mAb | SNCA inhibitor |
| cp6a | Modulator | experimental | Small molecule | SNCA modulator |
| npt200-11 | Stabiliser | experimental | Small molecule | SNCA stabiliser |
| zm-02 | Supplementation | experimental | Gene therapy | SNCA supplementation |