← Mechanisms of action

Dihydrofolate reductase

SINGLE PROTEINPlasmodium falciparum (isolate K1 / Thailand)

Linked proteins

Drugs acting on this target (2)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
proguanilInhibitorapprovedSmall moleculeDihydrofolate reductase inhibitor
pyrimethamine (daraprim)InhibitorapprovedSmall moleculeDihydrofolate reductase inhibitor