← Mechanisms of action
ACVR2A
SINGLE PROTEINHomo sapiens
Preferred name: Activin receptor type-2A ChEMBL ↗
Linked proteins
Drugs acting on this target (8)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| imc-003 | Activator | experimental | Recombinant protein | ACVR2A activator |
| bone morphogenetic protein-2 | Agonist | experimental | Recombinant protein | Activin receptor type-2A agonist |
| azd1043 | Inhibitor | experimental | Small molecule | ACVR2A inhibitor |
| hs135 | Inhibitor | experimental | Recombinant protein | ACVR2A inhibitor |
| ker-012 | Inhibitor | experimental | Recombinant protein | ACVR2A inhibitor |
| lae102 | Inhibitor | experimental | Small molecule | ACVR2A inhibitor |
| lae103 | Inhibitor | experimental | mAb | ACVR2A inhibitor |
| sotatercept (WINREVAIR) | Inhibitor | approved | Recombinant protein | ACVR2A inhibitor |