← Mechanisms of action
ACVR2B
SINGLE PROTEINHomo sapiens
Preferred name: Activin receptor type-2B ChEMBL ↗
Linked proteins
Drugs acting on this target (5)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| bone morphogenetic protein-2 | Agonist | experimental | Recombinant protein | Activin receptor type-2B agonist |
| bimagrumab | Antagonist | experimental | mAb | ACVR2B antagonist |
| luspatercept (Reblozyl) | Antagonist | approved | Recombinant protein | ACVR2B antagonist |
| ace-031 | Inhibitor | experimental | mAb | ACVR2B inhibitor |
| bimagrumab | Inhibitor | experimental | mAb | ACVR2B inhibitor |