← Mechanisms of action
CD38
SINGLE PROTEINHomo sapiens
Preferred name: Lymphocyte differentiation antigen CD38 ChEMBL ↗
Linked proteins
Drugs acting on this target (49)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| cid-103 | Adcc | experimental | mAb | CD38 |
| gen3014 | Adcc | experimental | mAb | CD38 |
| sg2501 | Antagonist | experimental | mAb | CD38 |
| tnb-738 | Antagonist | experimental | mAb | CD38 |
| daratumumab (darzalex) | Binding agent | approved | mAb | CD38 binding agent |
| igm-2644 | Binding agent | experimental | mAb | CD38 binding agent |
| isb 2001 | Binding agent | experimental | mAb | CD38 binding agent |
| mt-0169 | Binding agent | experimental | Recombinant protein | CD38 binding agent |
| okt10-b10 | Binding agent | experimental | mAb | CD38 |
| sar442257 | Binding agent | experimental | mAb | CD38 |
| tak-079 | Binding agent | experimental | mAb | Lymphocyte differentiation antigen CD38 binding agent |
| XMab-15426 | Binding agent | experimental | mAb | CD38 |
| xmab18968 | Binding agent | experimental | mAb | CD38 |
| y150 | Binding agent | experimental | mAb | CD38 |
| cart-38 cellls | Immunity, passive | experimental | Cell therapy | CD38 immunity, passive |
| cll1 and cd38 dual-target car-t injection | Immunity, passive | experimental | Cell therapy | CD38 immunity, passive |
| sti-1492 | Immunity, passive | experimental | Cell therapy | CD38 immunity, passive |
| abbv-438 | Inhibitor | experimental | mAb | CD38 inhibitor |
| anti-cd38 | Inhibitor | experimental | mAb | CD38 inhibitor |
| cm313 | Inhibitor | experimental | Small molecule | CD38 inhibitor |
| daratumumab (darzalex) | Inhibitor | approved | mAb | CD38 inhibitor |
| hlx15 | Inhibitor | experimental | mAb | CD38 inhibitor |
| Isatuximab (Sarclisa) | Inhibitor | approved | mAb | CD38 inhibitor |
| isb 1442 | Inhibitor | experimental | mAb | CD38 inhibitor |
| kp1237 | Inhibitor | experimental | mAb | CD38 inhibitor |
| lx102 | Inhibitor | experimental | Small molecule | CD38 inhibitor |
| mor202 | Inhibitor | experimental | mAb | Lymphocyte differentiation antigen CD38 inhibitor |
| prv-015 | Inhibitor | experimental | mAb | CD38 inhibitor |
| regn7945 | Inhibitor | experimental | mAb | CD38 inhibitor |
| sctc21c | Inhibitor | experimental | mAb | CD38 inhibitor |
| sg301 | Inhibitor | experimental | mAb | CD38 inhibitor |
| vp301 | Inhibitor | experimental | mAb | CD38 inhibitor |
| zg006 | Inhibitor | experimental | Small molecule | CD38 inhibitor |
| 89zr-amg211 | Radiopharmaceutical | experimental | mAb | CD38 radiopharmaceutical |
| 64cu-dota-daratumumab | Supplementation | experimental | mAb | CD38 supplementation |
| 89zr-dfo-daratumumab | Supplementation | experimental | mAb | CD38 supplementation |
| amg 424 | Supplementation | experimental | mAb | CD38 supplementation |
| daratumumab (darzalex) | Supplementation | approved | mAb | CD38 supplementation |
| gbr 1342 | Supplementation | experimental | mAb | CD38 supplementation |
| Isatuximab (Sarclisa) | Supplementation | approved | mAb | CD38 supplementation |
| jnj-70218902 | Supplementation | experimental | mAb | CD38 supplementation |
| mor03087 | Supplementation | experimental | mAb | CD38 supplementation |
| mor202 | Supplementation | experimental | mAb | CD38 supplementation |
| sar442085 | Supplementation | experimental | mAb | CD38 supplementation |
| sti-6129 | Supplementation | experimental | mAb | CD38 supplementation |
| tak-079 | Supplementation | experimental | mAb | CD38 supplementation |
| tak-169 | Supplementation | experimental | mAb | CD38 supplementation |
| tak-573 | Supplementation | experimental | mAb | CD38 supplementation |
| tj202 | Supplementation | experimental | mAb | CD38 supplementation |